FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2200619671> ?p ?o ?g. }

• W2200619671 endingPage "78" @default.
• W2200619671 startingPage "70" @default.
• W2200619671 abstract "Spinal cord and peripheral nerves are classically known to be damaged in Friedreich's ataxia, but the extent of cerebral involvement in the disease and its progression over time are not yet characterized. The aim of this study was to evaluate longitudinally cerebral damage in Friedreich's ataxia.We enrolled 31 patients and 40 controls, which were evaluated at baseline and after 1 and 2 years. To assess gray matter, we employed voxel-based morphometry and cortical thickness measurements. White matter was evaluated using diffusion tensor imaging. Statistical analyses were both cross-sectional and longitudinal (corrected for multiple comparisons).Group comparison between patients and controls revealed widespread macrostructural differences at baseline: gray matter atrophy in the dentate nuclei, brainstem, and precentral gyri; and white matter atrophy in the cerebellum and superior cerebellar peduncles, brainstem, and periventricular areas. We did not identify any longitudinal volumetric change over time. There were extensive microstructural alterations, including superior cerebellar peduncles, corpus callosum, and pyramidal tracts. Longitudinal analyses identified progressive microstructural abnormalities at the corpus callosum, pyramidal tracts, and superior cerebellar peduncles after 1 year of follow-up.Patients with Friedreich's ataxia present more widespread gray and white matter damage than previously reported, including not only infratentorial areas, but also supratentorial structures. Furthermore, patients with Friedreich's ataxia have progressive microstructural abnormalities amenable to detection in a short-term follow-up." @default.
• W2200619671 created "2016-06-24" @default.
• W2200619671 creator A5010357939 @default.
• W2200619671 creator A5013301045 @default.
• W2200619671 creator A5020192663 @default.
• W2200619671 creator A5026563901 @default.
• W2200619671 creator A5031524163 @default.
• W2200619671 creator A5044809264 @default.
• W2200619671 creator A5046046544 @default.
• W2200619671 creator A5059187961 @default.
• W2200619671 date "2015-12-21" @default.
• W2200619671 modified "2023-10-17" @default.
• W2200619671 title "Longitudinal magnetic resonance imaging study shows progressive pyramidal and callosal damage in Friedreich's ataxia" @default.
• W2200619671 cites W1982390702 @default.
• W2200619671 cites W1985093325 @default.
• W2200619671 cites W1985440423 @default.
• W2200619671 cites W1991353957 @default.
• W2200619671 cites W1994181706 @default.
• W2200619671 cites W2004293194 @default.
• W2200619671 cites W2005495240 @default.
• W2200619671 cites W2006096283 @default.
• W2200619671 cites W2012909868 @default.
• W2200619671 cites W2023085442 @default.
• W2200619671 cites W2023526105 @default.
• W2200619671 cites W2032019919 @default.
• W2200619671 cites W2035064536 @default.
• W2200619671 cites W2037368945 @default.
• W2200619671 cites W2046557060 @default.
• W2200619671 cites W2047905051 @default.
• W2200619671 cites W2053924346 @default.
• W2200619671 cites W2057926880 @default.
• W2200619671 cites W2060522888 @default.
• W2200619671 cites W2072515355 @default.
• W2200619671 cites W2072987789 @default.
• W2200619671 cites W2073880764 @default.
• W2200619671 cites W2082468728 @default.
• W2200619671 cites W2096464945 @default.
• W2200619671 cites W2097816953 @default.
• W2200619671 cites W2101135654 @default.
• W2200619671 cites W2103481737 @default.
• W2200619671 cites W2110208125 @default.
• W2200619671 cites W2112518510 @default.
• W2200619671 cites W2119423645 @default.
• W2200619671 cites W2119848633 @default.
• W2200619671 cites W2124710338 @default.
• W2200619671 cites W2142255966 @default.
• W2200619671 cites W2150667092 @default.
• W2200619671 cites W2155298532 @default.
• W2200619671 cites W2158155007 @default.
• W2200619671 cites W2168881248 @default.
• W2200619671 cites W4252041699 @default.
• W2200619671 doi "https://doi.org/10.1002/mds.26436" @default.
• W2200619671 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26688047" @default.
• W2200619671 hasPublicationYear "2015" @default.
• W2200619671 type Work @default.
• W2200619671 sameAs 2200619671 @default.
• W2200619671 citedByCount "40" @default.
• W2200619671 countsByYear W22006196712016 @default.
• W2200619671 countsByYear W22006196712017 @default.
• W2200619671 countsByYear W22006196712018 @default.
• W2200619671 countsByYear W22006196712019 @default.
• W2200619671 countsByYear W22006196712020 @default.
• W2200619671 countsByYear W22006196712021 @default.
• W2200619671 countsByYear W22006196712022 @default.
• W2200619671 countsByYear W22006196712023 @default.
• W2200619671 crossrefType "journal-article" @default.
• W2200619671 hasAuthorship W2200619671A5010357939 @default.
• W2200619671 hasAuthorship W2200619671A5013301045 @default.
• W2200619671 hasAuthorship W2200619671A5020192663 @default.
• W2200619671 hasAuthorship W2200619671A5026563901 @default.
• W2200619671 hasAuthorship W2200619671A5031524163 @default.
• W2200619671 hasAuthorship W2200619671A5044809264 @default.
• W2200619671 hasAuthorship W2200619671A5046046544 @default.
• W2200619671 hasAuthorship W2200619671A5059187961 @default.
• W2200619671 hasConcept C105702510 @default.
• W2200619671 hasConcept C126838900 @default.
• W2200619671 hasConcept C142724271 @default.
• W2200619671 hasConcept C143409427 @default.
• W2200619671 hasConcept C149550507 @default.
• W2200619671 hasConcept C15744967 @default.
• W2200619671 hasConcept C169760540 @default.
• W2200619671 hasConcept C200134340 @default.
• W2200619671 hasConcept C2778183499 @default.
• W2200619671 hasConcept C2779652256 @default.
• W2200619671 hasConcept C2780906641 @default.
• W2200619671 hasConcept C2781172350 @default.
• W2200619671 hasConcept C2781192897 @default.
• W2200619671 hasConcept C551621295 @default.
• W2200619671 hasConcept C71924100 @default.
• W2200619671 hasConceptScore W2200619671C105702510 @default.
• W2200619671 hasConceptScore W2200619671C126838900 @default.
• W2200619671 hasConceptScore W2200619671C142724271 @default.
• W2200619671 hasConceptScore W2200619671C143409427 @default.
• W2200619671 hasConceptScore W2200619671C149550507 @default.
• W2200619671 hasConceptScore W2200619671C15744967 @default.
• W2200619671 hasConceptScore W2200619671C169760540 @default.
• W2200619671 hasConceptScore W2200619671C200134340 @default.
• W2200619671 hasConceptScore W2200619671C2778183499 @default.

• next