FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2200796066> ?p ?o ?g. }

• W2200796066 endingPage "e2184" @default.
• W2200796066 startingPage "e2184" @default.
• W2200796066 abstract "Vaccination against Streptococcus pneumoniae is recommended for rheumatoid arthritis (RA) patients receiving immunosuppressive treatments. The objective of this study was to evaluate the humoral response to 23-valent pneumococcal polysaccharide vaccination (PPSV23) in RA patients receiving methotrexate (MTX) alone or in combination with a tumor necrosis factor inhibitor, golimumab (GOM). PPSV23 was given to 114 RA patients, who were classified into three groups: RA control (n = 35), MTX alone (n = 55), and GOM + MTX (n = 24). Before and 4 to 6 weeks after vaccination, concentrations of antibodies against pneumococcal serotypes 6B and 23F were measured using an enzyme-linked immunosorbent assay and antibody functionality was determined using a multiplexed opsonophagocytic killing assay, reported as the opsonization index (OI). The IgG concentrations and OIs were both significantly increased in all treatment groups in response to PPSV23 vaccination. In the GOM + MTX group, the IgG responses were lower than those in the MTX alone or control groups, whereas the OI responses were similar to those in the other 2 groups. Furthermore, discrepancies between the IgG and OI responses were found in GOM + MTX group. No severe adverse effect was observed in any treatment groups. OI responses indicate that antibody functionality rather than antibody quantity is important. The similarity of these measurements between all 3 groups suggests that RA patients receiving MTX + GOM still benefit from receiving the PPSV23 vaccination, even though they produce less IgG in response to it. These results can help clinicians to better schedule and evaluate pneumococcal vaccination for RA patients." @default.
• W2200796066 created "2016-06-24" @default.
• W2200796066 creator A5000020934 @default.
• W2200796066 creator A5001329573 @default.
• W2200796066 creator A5007448777 @default.
• W2200796066 creator A5010722823 @default.
• W2200796066 creator A5012013248 @default.
• W2200796066 creator A5014323872 @default.
• W2200796066 creator A5017221147 @default.
• W2200796066 creator A5019331714 @default.
• W2200796066 creator A5022460304 @default.
• W2200796066 creator A5023833652 @default.
• W2200796066 creator A5027558477 @default.
• W2200796066 creator A5029785146 @default.
• W2200796066 creator A5031205805 @default.
• W2200796066 creator A5033728193 @default.
• W2200796066 creator A5037094720 @default.
• W2200796066 creator A5038362333 @default.
• W2200796066 creator A5039472504 @default.
• W2200796066 creator A5040305440 @default.
• W2200796066 creator A5043738258 @default.
• W2200796066 creator A5046713223 @default.
• W2200796066 creator A5054279320 @default.
• W2200796066 creator A5054357289 @default.
• W2200796066 creator A5056222901 @default.
• W2200796066 creator A5057163448 @default.
• W2200796066 creator A5057574490 @default.
• W2200796066 creator A5062984817 @default.
• W2200796066 creator A5066579583 @default.
• W2200796066 creator A5071715246 @default.
• W2200796066 creator A5078824918 @default.
• W2200796066 creator A5079992475 @default.
• W2200796066 creator A5080687126 @default.
• W2200796066 creator A5087375127 @default.
• W2200796066 creator A5088100950 @default.
• W2200796066 creator A5088249757 @default.
• W2200796066 date "2015-12-01" @default.
• W2200796066 modified "2023-10-13" @default.
• W2200796066 title "Opsonic and Antibody Responses to Pneumococcal Polysaccharide in Rheumatoid Arthritis Patients Receiving Golimumab Plus Methotrexate" @default.
• W2200796066 cites W1498712623 @default.
• W2200796066 cites W1513110336 @default.
• W2200796066 cites W1869015705 @default.
• W2200796066 cites W1968001725 @default.
• W2200796066 cites W1988975600 @default.
• W2200796066 cites W1991484790 @default.
• W2200796066 cites W2011746735 @default.
• W2200796066 cites W2023284037 @default.
• W2200796066 cites W2028948634 @default.
• W2200796066 cites W2029962395 @default.
• W2200796066 cites W2062518619 @default.
• W2200796066 cites W2085947993 @default.
• W2200796066 cites W2087596125 @default.
• W2200796066 cites W2102990989 @default.
• W2200796066 cites W2106134483 @default.
• W2200796066 cites W2109091208 @default.
• W2200796066 cites W2109595158 @default.
• W2200796066 cites W2114386527 @default.
• W2200796066 cites W2123619196 @default.
• W2200796066 cites W2127849792 @default.
• W2200796066 cites W2135761651 @default.
• W2200796066 cites W2139125363 @default.
• W2200796066 cites W2142981860 @default.
• W2200796066 cites W2147507344 @default.
• W2200796066 cites W2154973129 @default.
• W2200796066 cites W2155237601 @default.
• W2200796066 cites W2156776857 @default.
• W2200796066 cites W2169904933 @default.
• W2200796066 cites W2337711227 @default.
• W2200796066 cites W3022405478 @default.
• W2200796066 cites W4297691726 @default.
• W2200796066 doi "https://doi.org/10.1097/md.0000000000002184" @default.
• W2200796066 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5291602" @default.
• W2200796066 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26717361" @default.
• W2200796066 hasPublicationYear "2015" @default.
• W2200796066 type Work @default.
• W2200796066 sameAs 2200796066 @default.
• W2200796066 citedByCount "12" @default.
• W2200796066 countsByYear W22007960662018 @default.
• W2200796066 countsByYear W22007960662019 @default.
• W2200796066 countsByYear W22007960662021 @default.
• W2200796066 countsByYear W22007960662022 @default.
• W2200796066 countsByYear W22007960662023 @default.
• W2200796066 crossrefType "journal-article" @default.
• W2200796066 hasAuthorship W2200796066A5000020934 @default.
• W2200796066 hasAuthorship W2200796066A5001329573 @default.
• W2200796066 hasAuthorship W2200796066A5007448777 @default.
• W2200796066 hasAuthorship W2200796066A5010722823 @default.
• W2200796066 hasAuthorship W2200796066A5012013248 @default.
• W2200796066 hasAuthorship W2200796066A5014323872 @default.
• W2200796066 hasAuthorship W2200796066A5017221147 @default.
• W2200796066 hasAuthorship W2200796066A5019331714 @default.
• W2200796066 hasAuthorship W2200796066A5022460304 @default.
• W2200796066 hasAuthorship W2200796066A5023833652 @default.
• W2200796066 hasAuthorship W2200796066A5027558477 @default.
• W2200796066 hasAuthorship W2200796066A5029785146 @default.
• W2200796066 hasAuthorship W2200796066A5031205805 @default.
• W2200796066 hasAuthorship W2200796066A5033728193 @default.
• W2200796066 hasAuthorship W2200796066A5037094720 @default.

• next