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- W2200796876 abstract "The perimenopause is a time of markedly fluctuating hormone levels. Attempts to define menopausal status purely on the basis of single measurements of FSH or E 2 are unlikely to yield useful information. Though E 2 concentrations appear to be preserved in regularly cycling women at least until the age of 50, INH-B declines and FSH rises. The establishment of menstrual irregularity is marked by a decrease in the follicular-phase concentrations of INH-B, an increase in FSH, but relative preservation of E 2 and INH-A until the time of the FMP. The frequency of anovulatory cycles increases markedly as the FMP approaches. It is difficult to demonstrate substantial changes in androgen concentrations in the immediate perimenopausal period, though levels postmenopausally appear to be lower than those of young regularly cycling women, perhaps as a function of increasing age rather than menopausal status. Hormonal measurements are of little diagnostic value during the perimenopause other than for the purposes of physiological study." @default.
- W2200796876 created "2016-06-24" @default.
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- W2200796876 date "2000-01-01" @default.
- W2200796876 modified "2023-09-27" @default.
- W2200796876 title "Perimenopausal Changes in FSH, the Inhibins, and the Circulating Steroid Hormone Milieu" @default.
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- W2200796876 doi "https://doi.org/10.1016/b978-012453790-3/50010-x" @default.
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