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- W2200934094 abstract "Means to quantitate cell-mediated immunity are increasingly in demand as modifications to existing vaccines and new vaccines are tested. For immunity to varicella zoster virus, there is over a decade of experience with estimates of responder cell frequency obtained by diluting the number of lymphocytes in antigen-stimulated cultures. This method shows substantial variations between subjects, so populations of 12 or more subjects per group are needed to make comparisons possible. Cytokine-based methods for T lymphocyte responses may prove more sensitive, as may direct antigen-binding methods using tetramers of peptide and histocompatibility antigens — but experience with both is very limited." @default.
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- W2200934094 date "2001-01-01" @default.
- W2200934094 modified "2023-09-23" @default.
- W2200934094 title "In vitro measurement of human T cell responses to varicella zoster virus antigen" @default.
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- W2200934094 doi "https://doi.org/10.1007/978-3-7091-6259-0_15" @default.
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