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- W2200935539 abstract "Background: HCM is an important cause of SCD under 35 yrs and is easily screened by ECG. Prognosis, presentation and severity of hypertrophy have a varied relation with ECG. Extent and prevalence of ECG abnormalities in HCM and their echo correlation is needed to clarify the ECG predictability of the Severity of hypertrophy. ECG categorization of severity would allow easy risk stratification of family members. Objective: Correlation between the ECG abnormalities and the maximum wall thickness, septal, lateral or apical, and the LVOTO gradients in echo is studied .ECG patterns and pattern of hypertrophy in echo also analysed Methods: maximum diastolic thickness of LV at any site more than 13mm and for the apical region more than or equal to 15mm was the criteria for hypertrophy. Measurement of septal thickness in diastole at the thickest part of septum and the other walls in PLAX - average of three M mode values used. Sixty newly diagnosed Hypertrophic cardiomyopathy patients during a 8 month out patient population in our hospital analysed. ECG anormality and distribution of LVH in echo are analysed. ECG abnormalities noted are LVH criteria (Cornell voltage and Sokolow Lyon), T inversions,abnormal Q wave . Results: LVH in ECG group , 50 patients (83%) had greater maximum septal or other wall thickness than the group with no LVH criteria in ECG 10(17%).Average wall thickness of 20± 4.87 mm v/s 17.8 ± 2.35mm p<0.101 in either group .ECG LVH was significantly associated with atleast moderate, ≥20 mm hypertrophy compared to mild hypertrophy only in no LVH in ECG group, p< 0.05.sensitivity of 93% but low specificity. Presence of abnormal Q wave was not a statistically significant marker of LVH ≥20mm. In Apical HCM subset of 18 pts ,V4 ,R wave of ≥20 mm and deep T inversion pattern was significantly associated compared to only 9 of 42 patients in non Apical subset p<0.001. Conclusions : LVH in ECG, predicted greater maximum septal/wall thickness by echo than patients without these ECG changes though p value <0.05 only.V4 R of ≥ 20 mm and deep T inversions in precordial leads pattern was quite specific for Apical HCM. Presence of deep abnormal Q waves, did not significantly correlate with increased septal thickness or LVOTO gradients p< 0.205." @default.
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- W2200935539 date "2012-07-20" @default.
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- W2200935539 title "ELECTROCARDIOGRAPHIC PATTERNS OF PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY AND THEIR ECHOCARDIOGRAPHIC CORRELATION" @default.
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