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- W2201511505 abstract "The investigations described in this review concern platelet adhesion and aggregation as blood flow-dependent phenomena. The experimental approach utilizes a chamber in which are controlled both blood flow and, in aggregation studies, the rate at which ADP enters flowing blood by localized diffusion through a Cuprophan membrane. Videomicroscopy and densitometry of video recordings allow quantification of the in situ growth of surface-adherent platelet aggregates. Platelet adhesion is studied separately using phase contrast microscopy. As a result, with the present method one can distinguish adhesion from aggregation, utilize whole blood, simulate arterial (or extracorporeal) shear rate conditions, independently vary ADP entry rate, and quantify aggregate growth in situ continuously." @default.
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- W2201511505 date "1978-01-01" @default.
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- W2201511505 title "Roles of Blood Flow in Platelet Adhesion and Aggregation" @default.
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- W2201511505 doi "https://doi.org/10.1007/978-1-4757-1217-9_5" @default.
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