Matches in SemOpenAlex for { <https://semopenalex.org/work/W2201613206> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2201613206 abstract "Publisher Summary This chapter discusses the molecular modification of renal brush border maltase with age. Maltase (α-D-glucoside glucohydrolase) is the major disaccharidase in rat renal brush border membranes. Maltase-specific activities in renal cortex homogenates and brush border membranes prepared from senescent 24-month-old rats are decreased 30–40% relative to the activities of the enzyme from 6-month-old mature adults. This decrement is not attributable to a change in the affinity of the enzyme for substrate, a difference in the stability of the enzyme in homogenates, or the presence of an activator in the young or an inhibitor in the aged. The chapter discusses whether the decrease in the membrane-bound maltase activity with age results from an alteration in the enzyme protein per se or from a change in the enzyme's membrane environment, which is reflected secondarily as a loss in enzyme activity. The results exhibit that the antigenicity of renal brush border membrane maltase is altered during the aging process. These findings indicate that young and old maltase has different epitopes and, thus, the data are consistent with and may reflect the age-dependent conformational change of the enzyme, suggested by the alteration in its circular dichroism spectrum." @default.
- W2201613206 created "2016-06-24" @default.
- W2201613206 creator A5053046636 @default.
- W2201613206 creator A5081203931 @default.
- W2201613206 date "1984-01-01" @default.
- W2201613206 modified "2023-09-26" @default.
- W2201613206 title "Chapter 13 Molecular Modification of Renal Brush Border Maltase with Age: Monoclonal Antibody-Specific Forms of the Enzyme" @default.
- W2201613206 cites W1970305201 @default.
- W2201613206 cites W1970863961 @default.
- W2201613206 cites W1990615139 @default.
- W2201613206 cites W1994742546 @default.
- W2201613206 cites W2022676745 @default.
- W2201613206 cites W2030522563 @default.
- W2201613206 cites W2045711765 @default.
- W2201613206 cites W2061353988 @default.
- W2201613206 cites W2073138802 @default.
- W2201613206 cites W2084855813 @default.
- W2201613206 doi "https://doi.org/10.1016/s0070-2161(08)60880-1" @default.
- W2201613206 hasPublicationYear "1984" @default.
- W2201613206 type Work @default.
- W2201613206 sameAs 2201613206 @default.
- W2201613206 citedByCount "0" @default.
- W2201613206 crossrefType "book-chapter" @default.
- W2201613206 hasAuthorship W2201613206A5053046636 @default.
- W2201613206 hasAuthorship W2201613206A5081203931 @default.
- W2201613206 hasConcept C126322002 @default.
- W2201613206 hasConcept C130316041 @default.
- W2201613206 hasConcept C134018914 @default.
- W2201613206 hasConcept C146201443 @default.
- W2201613206 hasConcept C181199279 @default.
- W2201613206 hasConcept C185592680 @default.
- W2201613206 hasConcept C2778649499 @default.
- W2201613206 hasConcept C28212737 @default.
- W2201613206 hasConcept C41625074 @default.
- W2201613206 hasConcept C5426402 @default.
- W2201613206 hasConcept C55493867 @default.
- W2201613206 hasConcept C71924100 @default.
- W2201613206 hasConcept C86803240 @default.
- W2201613206 hasConceptScore W2201613206C126322002 @default.
- W2201613206 hasConceptScore W2201613206C130316041 @default.
- W2201613206 hasConceptScore W2201613206C134018914 @default.
- W2201613206 hasConceptScore W2201613206C146201443 @default.
- W2201613206 hasConceptScore W2201613206C181199279 @default.
- W2201613206 hasConceptScore W2201613206C185592680 @default.
- W2201613206 hasConceptScore W2201613206C2778649499 @default.
- W2201613206 hasConceptScore W2201613206C28212737 @default.
- W2201613206 hasConceptScore W2201613206C41625074 @default.
- W2201613206 hasConceptScore W2201613206C5426402 @default.
- W2201613206 hasConceptScore W2201613206C55493867 @default.
- W2201613206 hasConceptScore W2201613206C71924100 @default.
- W2201613206 hasConceptScore W2201613206C86803240 @default.
- W2201613206 hasLocation W22016132061 @default.
- W2201613206 hasOpenAccess W2201613206 @default.
- W2201613206 hasPrimaryLocation W22016132061 @default.
- W2201613206 hasRelatedWork W1544176401 @default.
- W2201613206 hasRelatedWork W1979855872 @default.
- W2201613206 hasRelatedWork W1995869756 @default.
- W2201613206 hasRelatedWork W2014889799 @default.
- W2201613206 hasRelatedWork W2018047864 @default.
- W2201613206 hasRelatedWork W2027828811 @default.
- W2201613206 hasRelatedWork W2053031410 @default.
- W2201613206 hasRelatedWork W2054289560 @default.
- W2201613206 hasRelatedWork W2059625272 @default.
- W2201613206 hasRelatedWork W2060137148 @default.
- W2201613206 hasRelatedWork W2073138802 @default.
- W2201613206 hasRelatedWork W2079798742 @default.
- W2201613206 hasRelatedWork W2196154026 @default.
- W2201613206 hasRelatedWork W2342791616 @default.
- W2201613206 hasRelatedWork W2397019997 @default.
- W2201613206 hasRelatedWork W2398899029 @default.
- W2201613206 hasRelatedWork W2417581392 @default.
- W2201613206 hasRelatedWork W2417768707 @default.
- W2201613206 hasRelatedWork W2464968221 @default.
- W2201613206 hasRelatedWork W3144361901 @default.
- W2201613206 isParatext "false" @default.
- W2201613206 isRetracted "false" @default.
- W2201613206 magId "2201613206" @default.
- W2201613206 workType "book-chapter" @default.