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- W2201616076 abstract "Iron is essential for life. Its coordinated distribution between intracellular compartments and the adaptation of iron uptake to intracellular demands are central for a balanced iron homeostasis. Mitochondria take center stage in cellular iron metabolism as they harbor the two major iron-utilizing pathways, the synthesis of heme and the biogenesis of iron-sulfur (Fe/S) proteins. Consistent with this central role, mitochondria are also critical regulators of cellular iron homeostasis. They directly influence cellular iron uptake and the status of iron-utilizing metabolic processes through iron-dependent co-factors or by control of gene expression. For all these aspects of cellular iron metabolism, the uptake of iron into mitochondria is critical. During the last decade, considerable progress has been made with respect to the functional characterization of mitochondrial iron acquisition and the identification of transporters involved. The model organism Saccharomyces cerevisiae has been especially useful for the elucidation of this process. Here, we summarize the recent advances in the mechanism of mitochondrial iron transport and the impact of mitochondria on the regulation of cellular iron homeostasis." @default.
- W2201616076 created "2016-06-24" @default.
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- W2201616076 date "2015-07-01" @default.
- W2201616076 modified "2023-10-18" @default.
- W2201616076 title "Compartmentalization of iron between mitochondria and the cytosol and its regulation" @default.
- W2201616076 cites W1484379620 @default.
- W2201616076 cites W1606683217 @default.
- W2201616076 cites W1678114481 @default.
- W2201616076 cites W170154559 @default.
- W2201616076 cites W1737772948 @default.
- W2201616076 cites W1911724401 @default.
- W2201616076 cites W1965021143 @default.
- W2201616076 cites W1965389900 @default.
- W2201616076 cites W1965754377 @default.
- W2201616076 cites W1967140535 @default.
- W2201616076 cites W1967432418 @default.
- W2201616076 cites W1967855521 @default.
- W2201616076 cites W1968347019 @default.
- W2201616076 cites W1969222453 @default.
- W2201616076 cites W1969743438 @default.
- W2201616076 cites W1970750229 @default.
- W2201616076 cites W1970761716 @default.
- W2201616076 cites W1972547633 @default.
- W2201616076 cites W1972998779 @default.
- W2201616076 cites W1974844038 @default.
- W2201616076 cites W1976725682 @default.
- W2201616076 cites W1977203945 @default.
- W2201616076 cites W1977328986 @default.
- W2201616076 cites W1977523943 @default.
- W2201616076 cites W1977890183 @default.
- W2201616076 cites W1978422105 @default.
- W2201616076 cites W1979628099 @default.
- W2201616076 cites W1981336649 @default.
- W2201616076 cites W1981407334 @default.
- W2201616076 cites W1983653026 @default.
- W2201616076 cites W1984197098 @default.
- W2201616076 cites W1984364185 @default.
- W2201616076 cites W1986119180 @default.
- W2201616076 cites W1986515003 @default.
- W2201616076 cites W1987704635 @default.
- W2201616076 cites W1988377666 @default.
- W2201616076 cites W1990120691 @default.
- W2201616076 cites W1991304993 @default.
- W2201616076 cites W1991349275 @default.
- W2201616076 cites W1991852898 @default.
- W2201616076 cites W1992193197 @default.
- W2201616076 cites W1992758160 @default.
- W2201616076 cites W1993779780 @default.
- W2201616076 cites W1995039474 @default.
- W2201616076 cites W1997734311 @default.
- W2201616076 cites W1998417732 @default.
- W2201616076 cites W1999699035 @default.
- W2201616076 cites W2000404166 @default.
- W2201616076 cites W2000988465 @default.
- W2201616076 cites W2001069236 @default.
- W2201616076 cites W2003418336 @default.
- W2201616076 cites W2004218239 @default.
- W2201616076 cites W2004525492 @default.
- W2201616076 cites W2005075246 @default.
- W2201616076 cites W2006247279 @default.
- W2201616076 cites W2006358233 @default.
- W2201616076 cites W2007468135 @default.
- W2201616076 cites W2007807161 @default.
- W2201616076 cites W2007919022 @default.
- W2201616076 cites W2008376250 @default.
- W2201616076 cites W2008895037 @default.
- W2201616076 cites W2010398938 @default.
- W2201616076 cites W2010802040 @default.
- W2201616076 cites W2012291035 @default.
- W2201616076 cites W2013375812 @default.
- W2201616076 cites W2014702774 @default.
- W2201616076 cites W2015661045 @default.
- W2201616076 cites W2017732115 @default.
- W2201616076 cites W2018411741 @default.
- W2201616076 cites W2018418293 @default.
- W2201616076 cites W2021910662 @default.
- W2201616076 cites W2021969604 @default.
- W2201616076 cites W2022758805 @default.
- W2201616076 cites W2023679821 @default.
- W2201616076 cites W2027163470 @default.
- W2201616076 cites W2028277996 @default.
- W2201616076 cites W2029473695 @default.
- W2201616076 cites W2029915182 @default.
- W2201616076 cites W2030122064 @default.
- W2201616076 cites W2031508994 @default.
- W2201616076 cites W2032088197 @default.
- W2201616076 cites W2035410822 @default.
- W2201616076 cites W2037024816 @default.
- W2201616076 cites W2037112564 @default.
- W2201616076 cites W2038405260 @default.