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• W2201802009 abstract "A silk fibroin (SF)-derived nanofibrous drug delivery system was fabricated by solution-enhanced dispersion via supercritical CO2 (SEDS) (20 MPa pressure, 8 mL/min flow rate, 35 °C temperature) in this study. Curcumin (CM) was used as a water-insoluble drug model. Nanofibrous structure with controllable fiber diameter (<100 nm) was obtained, and inter-molecular hydrogen bonds were formed between CM and SF; the crystallinity of the incorporated CM was remarkably decreased, which led to a significant enhancement in solubility of incorporated CM. In conclusion, SEDS could be developed to fabricate polymeric nanofibrous drug delivery system." @default.
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• W2201802009 date "2016-03-01" @default.
• W2201802009 modified "2023-10-09" @default.
• W2201802009 title "Development of silk fibroin-derived nanofibrous drug delivery system in supercritical CO2" @default.
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• W2201802009 doi "https://doi.org/10.1016/j.matlet.2015.12.151" @default.
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