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• W2201871812 abstract "Alzheimer’s (AD) and Parkinson’s (PD) diseases are devastating neurodegenerative disturbances wherein neuroinflammation is a chronic pathogenic process with high therapeutic potential. Major mediators of AD/PD neuroimmune processes are resident immune cells, but immune cells derived from periphery may also participate and to some extent modify neuroinflammation. Specifically, blood borne myeloid cells emerge as crucial components of AD/PD progression and susceptibility. Among these, dendritic cells (DCs) are key immune orchestrators and players of brain immune surveillance: we candidate them as potential mediators of both AD and PD and as relevant cell model for unraveling myeloid cell role in neurodegeneration. Hence, we recapitulate and discuss emerging data suggesting that blood-derived DCs play a role in experimental and human neurodegenerative diseases. In humans, in particular, DCs are modified by in vitro culture with neurodegeneration-associated pathogenic factors and dysregulated in AD patients, while the levels of DC precursors are decreased in AD and PD patients’ blood, possibly as an index of their recruitment to the brain. Overall, we emphasize the need to explore the impact of DCs on neurodegeneration to uncover peripheral immune mechanisms of pathogenic importance, recognize potential biomarkers and improve therapeutic approaches for neurodegenerative diseases." @default.
• W2201871812 created "2016-06-24" @default.
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• W2201871812 date "2015-12-16" @default.
• W2201871812 modified "2023-09-26" @default.
• W2201871812 title "Myeloid Dendritic Cells are Potential Players in Human Neurodegenerative Diseases" @default.
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• W2201871812 cites W1595078459 @default.
• W2201871812 cites W1598703170 @default.
• W2201871812 cites W1607135210 @default.
• W2201871812 cites W1611537194 @default.
• W2201871812 cites W1722844298 @default.
• W2201871812 cites W1824528965 @default.
• W2201871812 cites W1841850981 @default.
• W2201871812 cites W1897859562 @default.
• W2201871812 cites W1916959962 @default.
• W2201871812 cites W1964117773 @default.
• W2201871812 cites W1964944610 @default.
• W2201871812 cites W1965942744 @default.
• W2201871812 cites W1967399741 @default.
• W2201871812 cites W1967640115 @default.
• W2201871812 cites W1975365037 @default.
• W2201871812 cites W1979038308 @default.
• W2201871812 cites W1984378291 @default.
• W2201871812 cites W1986710534 @default.
• W2201871812 cites W1992481658 @default.
• W2201871812 cites W1993829231 @default.
• W2201871812 cites W1999722943 @default.
• W2201871812 cites W1999794509 @default.
• W2201871812 cites W2003612310 @default.
• W2201871812 cites W2006035554 @default.
• W2201871812 cites W2014272598 @default.
• W2201871812 cites W2017003937 @default.
• W2201871812 cites W2031924346 @default.
• W2201871812 cites W2038177416 @default.
• W2201871812 cites W2038197998 @default.
• W2201871812 cites W2038460036 @default.
• W2201871812 cites W2041069911 @default.
• W2201871812 cites W2041690090 @default.
• W2201871812 cites W2047704857 @default.
• W2201871812 cites W2048143404 @default.
• W2201871812 cites W2053313675 @default.
• W2201871812 cites W2053346970 @default.
• W2201871812 cites W2058669152 @default.
• W2201871812 cites W2059996790 @default.
• W2201871812 cites W2067365613 @default.
• W2201871812 cites W2069350334 @default.
• W2201871812 cites W2071753918 @default.
• W2201871812 cites W2072027025 @default.
• W2201871812 cites W2072096009 @default.
• W2201871812 cites W2074405990 @default.
• W2201871812 cites W2077215378 @default.
• W2201871812 cites W2078324786 @default.
• W2201871812 cites W2081117923 @default.
• W2201871812 cites W2081845571 @default.
• W2201871812 cites W2082429191 @default.
• W2201871812 cites W2087243986 @default.
• W2201871812 cites W2088315776 @default.
• W2201871812 cites W2093455511 @default.
• W2201871812 cites W2093874807 @default.
• W2201871812 cites W2097867538 @default.
• W2201871812 cites W2098393992 @default.
• W2201871812 cites W2101280135 @default.
• W2201871812 cites W2102416906 @default.
• W2201871812 cites W2111464898 @default.
• W2201871812 cites W2112526127 @default.
• W2201871812 cites W2112880160 @default.
• W2201871812 cites W2123937957 @default.
• W2201871812 cites W2128613449 @default.
• W2201871812 cites W2131761283 @default.
• W2201871812 cites W2132565242 @default.
• W2201871812 cites W2132884035 @default.
• W2201871812 cites W2133096503 @default.
• W2201871812 cites W2135833206 @default.
• W2201871812 cites W2137599689 @default.
• W2201871812 cites W2139406641 @default.
• W2201871812 cites W2140139281 @default.
• W2201871812 cites W2145938600 @default.
• W2201871812 cites W2151513507 @default.
• W2201871812 cites W2154349779 @default.
• W2201871812 cites W2155009321 @default.
• W2201871812 cites W2155344647 @default.
• W2201871812 cites W2155737332 @default.
• W2201871812 cites W2156944982 @default.
• W2201871812 cites W2165738847 @default.
• W2201871812 cites W2170392479 @default.
• W2201871812 cites W2316522881 @default.
• W2201871812 doi "https://doi.org/10.3389/fimmu.2015.00632" @default.
• W2201871812 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4679857" @default.
• W2201871812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26734003" @default.
• W2201871812 hasPublicationYear "2015" @default.
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