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- W2201943415 abstract "Rectal cancer treatment has witnessed several changes in the past decades resulting into improved outcomes. 1 Brenner H. Kloor M. Pox C.P. Colorectal cancer. Lancet. Apr 26 2014; 383: 1490-1502 Abstract Full Text Full Text PDF PubMed Scopus (2162) Google Scholar Pre-operative radiotherapy is much better tolerated than post-operative radiotherapy, and the combination with chemotherapy has proven to be very effective in downstaging rectal cancer. Implementation of standard baseline MRI staging has enabled a better selection of high risk patients who will benefit from neoadjuvant (chemo) radiation (ChRT). The recognition that histological features of the resection specimen are powerful prognostic tools helped to optimize the surgical technique into the current standard of Total Mesorectal Excision (TME). Additionally, auditing and feeding back the performance has improved surgical quality and decreased the local relapse rate. With all these changes, local control is no longer the Achilles heel in rectal cancer treatment." @default.
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- W2201943415 date "2015-12-01" @default.
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- W2201943415 title "A new paradigm for rectal cancer: Organ preservation" @default.
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- W2201943415 doi "https://doi.org/10.1016/j.ejso.2015.09.008" @default.
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