Matches in SemOpenAlex for { <https://semopenalex.org/work/W2201992640> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2201992640 abstract "This study reports the initial in vivo use of a combined radiofrequency ablation and cryo-anchoring (RFC) catheter as an alternative to surgical mitral valve (MV) leaflet resection. Radiofrequency ablation thermally shrinks enlarged collagenous tissues, providing an alternative to leaflet resection, and cryo-anchoring provides reversible attachment of a catheter to freely mobile MV leaflets. Excised porcine MVs (n = 9) were tested in a left heart flow simulator to establish treatment efficacy criteria. Resected leaflet area was quantified by tracking markers on the leaflet surface, and leaflet length reductions were directly measured on echocardiography. Leaflet area decreased by 38 ± 2.7%, and leaflet length decreased by 9.2 ± 1.8% following RFC catheter treatment. The RFC catheter was then tested acutely in healthy pigs (n = 5) under epicardial echocardiographic guidance, open-chest without cardiopulmonary bypass, using mid-ventricular free wall access. Leaflet length was quantified using echocardiography. Quantitative assessment of MV leaflet length revealed that leaflet resection was successful in 4 of 5 pigs, with a leaflet length reduction of 13.3 ± 4.6%. Histological, mechanical, and gross pathological findings also confirmed that RFC catheter treatment was efficacious. The RFC catheter significantly reduces MV leaflet size in an acute animal model, providing a possible percutaneous alternative to surgical leaflet resection." @default.
- W2201992640 created "2016-06-24" @default.
- W2201992640 creator A5006943398 @default.
- W2201992640 creator A5028857635 @default.
- W2201992640 creator A5042548894 @default.
- W2201992640 creator A5056744123 @default.
- W2201992640 creator A5062184642 @default.
- W2201992640 creator A5079036287 @default.
- W2201992640 creator A5082087932 @default.
- W2201992640 date "2015-10-27" @default.
- W2201992640 modified "2023-09-25" @default.
- W2201992640 title "Quantitative Imaging Assessment of an Alternative Approach to Surgical Mitral Valve Leaflet Resection: An Acute Porcine Study" @default.
- W2201992640 cites W163303675 @default.
- W2201992640 cites W1976397091 @default.
- W2201992640 cites W2006797531 @default.
- W2201992640 cites W2031904589 @default.
- W2201992640 cites W2035274296 @default.
- W2201992640 cites W2051229774 @default.
- W2201992640 cites W2063870673 @default.
- W2201992640 cites W2073832004 @default.
- W2201992640 cites W2078401633 @default.
- W2201992640 cites W2106089315 @default.
- W2201992640 cites W2110137534 @default.
- W2201992640 cites W2123428520 @default.
- W2201992640 cites W2143698378 @default.
- W2201992640 cites W2155699373 @default.
- W2201992640 cites W2480924511 @default.
- W2201992640 doi "https://doi.org/10.1007/s10439-015-1494-1" @default.
- W2201992640 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4848187" @default.
- W2201992640 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26508331" @default.
- W2201992640 hasPublicationYear "2015" @default.
- W2201992640 type Work @default.
- W2201992640 sameAs 2201992640 @default.
- W2201992640 citedByCount "1" @default.
- W2201992640 countsByYear W22019926402020 @default.
- W2201992640 crossrefType "journal-article" @default.
- W2201992640 hasAuthorship W2201992640A5006943398 @default.
- W2201992640 hasAuthorship W2201992640A5028857635 @default.
- W2201992640 hasAuthorship W2201992640A5042548894 @default.
- W2201992640 hasAuthorship W2201992640A5056744123 @default.
- W2201992640 hasAuthorship W2201992640A5062184642 @default.
- W2201992640 hasAuthorship W2201992640A5079036287 @default.
- W2201992640 hasAuthorship W2201992640A5082087932 @default.
- W2201992640 hasBestOaLocation W22019926402 @default.
- W2201992640 hasConcept C141071460 @default.
- W2201992640 hasConcept C151730666 @default.
- W2201992640 hasConcept C164705383 @default.
- W2201992640 hasConcept C2776131983 @default.
- W2201992640 hasConcept C2776659728 @default.
- W2201992640 hasConcept C2777377203 @default.
- W2201992640 hasConcept C2777543888 @default.
- W2201992640 hasConcept C2778881276 @default.
- W2201992640 hasConcept C2778902805 @default.
- W2201992640 hasConcept C2780813298 @default.
- W2201992640 hasConcept C2781267111 @default.
- W2201992640 hasConcept C71924100 @default.
- W2201992640 hasConcept C86803240 @default.
- W2201992640 hasConceptScore W2201992640C141071460 @default.
- W2201992640 hasConceptScore W2201992640C151730666 @default.
- W2201992640 hasConceptScore W2201992640C164705383 @default.
- W2201992640 hasConceptScore W2201992640C2776131983 @default.
- W2201992640 hasConceptScore W2201992640C2776659728 @default.
- W2201992640 hasConceptScore W2201992640C2777377203 @default.
- W2201992640 hasConceptScore W2201992640C2777543888 @default.
- W2201992640 hasConceptScore W2201992640C2778881276 @default.
- W2201992640 hasConceptScore W2201992640C2778902805 @default.
- W2201992640 hasConceptScore W2201992640C2780813298 @default.
- W2201992640 hasConceptScore W2201992640C2781267111 @default.
- W2201992640 hasConceptScore W2201992640C71924100 @default.
- W2201992640 hasConceptScore W2201992640C86803240 @default.
- W2201992640 hasFunder F4320306230 @default.
- W2201992640 hasFunder F4320306300 @default.
- W2201992640 hasLocation W22019926401 @default.
- W2201992640 hasLocation W22019926402 @default.
- W2201992640 hasLocation W22019926403 @default.
- W2201992640 hasLocation W22019926404 @default.
- W2201992640 hasOpenAccess W2201992640 @default.
- W2201992640 hasPrimaryLocation W22019926401 @default.
- W2201992640 hasRelatedWork W1998670837 @default.
- W2201992640 hasRelatedWork W2019367937 @default.
- W2201992640 hasRelatedWork W2035272747 @default.
- W2201992640 hasRelatedWork W2047755126 @default.
- W2201992640 hasRelatedWork W2058916590 @default.
- W2201992640 hasRelatedWork W2061731767 @default.
- W2201992640 hasRelatedWork W2098757653 @default.
- W2201992640 hasRelatedWork W2108827968 @default.
- W2201992640 hasRelatedWork W2117319771 @default.
- W2201992640 hasRelatedWork W2129664159 @default.
- W2201992640 hasRelatedWork W2136108059 @default.
- W2201992640 hasRelatedWork W2136736503 @default.
- W2201992640 hasRelatedWork W2146064622 @default.
- W2201992640 hasRelatedWork W2147930285 @default.
- W2201992640 hasRelatedWork W2150476661 @default.
- W2201992640 hasRelatedWork W2618692528 @default.
- W2201992640 hasRelatedWork W776959778 @default.
- W2201992640 isParatext "false" @default.
- W2201992640 isRetracted "false" @default.
- W2201992640 magId "2201992640" @default.
- W2201992640 workType "article" @default.