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- W2202642114 abstract "Objective Although sleep impairment is reported by patients with chronic rhinosinusitis, the associated factors have not been well studied. Therefore, we determined the associated risk factors for sleep impairment in patients with chronic rhinosinusitis (CRS). Methods This study was a prospective cohort study. A total of 572 adult patients (171 women, 401 men; mean age, 49.0 years; range, 18–64 years) who completed a questionnaire, had a clinical examination, and underwent endoscopic sinus surgery were analyzed using stepwise multiple linear regression. Results With regard to subjective symptoms, nasal obstruction (beta coef., 0.27; p < 0.001), anterior nasal drainage (beta coef., 0.13; p = 0.004), facial pain/pressure (beta coef., 0.09; p = 0.048), headache (beta coef., 0.10; p = 0.010), and cough (beta coef., 0.14; p < 0.001) were predictors of an increased risk of sleep impairment of CRS (adjusted R2, 0.240; p = 0.048). In the matter of background parameters, total polyp score (polyp grading system) (beta coef., 0.16; p < 0.001) and allergic rhinitis (beta coef., 0.09; p = 0.034) were predictors of an increased risk of sleep impairment of CRS (adjusted R2, 0.029; p = 0.034). Conclusion These results suggest that sleep impairment in these patients is caused by the various mechanisms associated with nasal symptoms themselves, CRS and allergic rhinitis. However, the specific pathophysiology has not been clarified yet; further studies are expected to elucidate that of sleep impairment in patients with CRS." @default.
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- W2202642114 date "2016-08-01" @default.
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- W2202642114 title "Risk factors for sleep impairment in adult patients with chronic rhinosinusitis" @default.
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- W2202642114 doi "https://doi.org/10.1016/j.anl.2015.10.006" @default.
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