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• W2202656811 abstract "The methanolic extract and its subfractions from red peony root, the dried roots of Paeonia lactiflora Pallas showed potent antiallergic effects, as inhibition of immunoglobulin E (IgE)-mediated degranulation in rat basophil leukemia (RBL)-2H3 cells. Bioassay-guided fractionation led to the isolation of 16 monoterpene derivatives, including 3 new compounds, paeoniflorol (1), 4'-hydroxypaeoniflorigenone (2) and 4-epi-albiflorin (3), together with 13 known ones (4-16). The chemical structures of the new compounds were elucidated on the basis of spectroscopic and chemical evidences. Among the isolated monoterpene derivatives, nine compounds showed potent anti-allergic effects and compound 1 was the most effective. A primary structure-activity relationship of monoterpene derivatives was discussed." @default.
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• W2202656811 date "2016-01-01" @default.
• W2202656811 modified "2023-10-12" @default.
• W2202656811 title "Monoterpene derivatives with anti-allergic activity from red peony root, the root of Paeonia lactiflora" @default.
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• W2202656811 doi "https://doi.org/10.1016/j.fitote.2015.11.011" @default.
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