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- W220282962 abstract "OKT3, a monoclonal antibody against the CD3 cell population, was introduced to hepatic transplantation in the mid-1980s for the treatment of steroid resistant rejection (1–3). For didactic purposes, the indications for OKT3 therapy may be divided into three broad categories: 1) as a rescue therapy for steroid resistant rejection; 2) as prophylactic (induction) therapy; and, 3) as the initial therapy of rejection with the goal of eliminating high doses of steroids during the period of convalescence. The results for the first two indications have been the subject of several publications (1–4) and will not be addressed in this manuscript. Instead, we will report our experience with the use of OKT3 for the initial treatment of rejection. In addition, our experience with the use of this monoclonal antibody in patients with postoperative renal failure, positive crossmatches or ABO incompatibility will also be reported." @default.
- W220282962 created "2016-06-24" @default.
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- W220282962 date "1993-01-01" @default.
- W220282962 modified "2023-09-27" @default.
- W220282962 title "Practical Uses of OKT3" @default.
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- W220282962 doi "https://doi.org/10.1007/978-94-011-1994-8_23" @default.
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