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- W2203403679 abstract "Bioassay-guided fractionation of the 60% ethanol extract of the stems of Calophyllum membranaceum using the RXRα transcription activation assay led to the isolation of two new chromanones, calopolyanic acid methyl ester (1) and isopinetoric acid methyl ester (2), two new xanthones, calophylixanthones A–B (3–4), and one new C-glycoside, calophymembranside C (5), along with 13 known compounds. Their structures were elucidated on the basis of extensive spectroscopic data. Compounds 5, 11 and 18 showed transcriptional inhibitory activity of RXRα with 50% inhibitory concentration (IC50) values of 29.95 ± 1.08, 31.06 ± 9.02, and 25.88 ± 1.62 μM, respectively." @default.
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- W2203403679 date "2016-01-01" @default.
- W2203403679 modified "2023-09-27" @default.
- W2203403679 title "RXRα transcriptional inhibitors from the stems of Calophyllum membranaceum" @default.
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- W2203403679 doi "https://doi.org/10.1016/j.fitote.2015.11.001" @default.
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