Matches in SemOpenAlex for { <https://semopenalex.org/work/W2203600014> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2203600014 endingPage "9" @default.
- W2203600014 startingPage "1481" @default.
- W2203600014 abstract "Rats progressively develop proteinuria and glomerular sclerosis with age. These physiologic and histologic changes are accelerated by subtotal renal mass ablation. Alterations in the glomerular basement membrane (GBM), such as thickening and decreased anionic site density, occur during senescence. This study examines the ultrastructural alterations of the GBM affecting remnant glomeruli. Six week-old male Wistar rats underwent a subtotal nephrectomy (70%) and were compared with sham operated rats. Rats were fed a standard diet, and physiologic measurements were performed every 3 weeks. Rats were killed 6 and 12 weeks after surgery. Anionic sites were labeled by polyethyleneimine perfusion before killing. Kidneys were processed for light and electron microscopy. Nephrectomized rats had higher protein-uria than the controls and developed glomerular sclerosis. The GBM of nephrectomized rats were significantly thinner and anionic sites were less numerous 12 weeks after nephrectomy, especially in the lamina densa (LD) of the GBM. The number and distribution of anionic sites were similar to those observed in sham operated rats killed 6 weeks after surgery. These results indicate that glomerular sclerosis and GBM thickening are unrelated phenomena. They also suggest that the number and density of anionic sites in LD are not a prominent factor for increasing proteinuria after subtotal nephrectomy." @default.
- W2203600014 created "2016-06-24" @default.
- W2203600014 creator A5033043946 @default.
- W2203600014 creator A5052687060 @default.
- W2203600014 creator A5066024242 @default.
- W2203600014 creator A5085890251 @default.
- W2203600014 creator A5089038480 @default.
- W2203600014 date "1992-12-01" @default.
- W2203600014 modified "2023-10-01" @default.
- W2203600014 title "Changes in thickness and anionic sites of the glomerular basement membrane after subtotal nephrectomy in the rat." @default.
- W2203600014 cites W1269748144 @default.
- W2203600014 cites W1590233037 @default.
- W2203600014 cites W16898192 @default.
- W2203600014 cites W1789261902 @default.
- W2203600014 cites W1843089250 @default.
- W2203600014 cites W1964676918 @default.
- W2203600014 cites W1970672884 @default.
- W2203600014 cites W1978891183 @default.
- W2203600014 cites W1985133368 @default.
- W2203600014 cites W2010961267 @default.
- W2203600014 cites W2027161422 @default.
- W2203600014 cites W2027785852 @default.
- W2203600014 cites W2040961193 @default.
- W2203600014 cites W2050723015 @default.
- W2203600014 cites W2055296168 @default.
- W2203600014 cites W2057916427 @default.
- W2203600014 cites W2060612610 @default.
- W2203600014 cites W2063928700 @default.
- W2203600014 cites W2077400092 @default.
- W2203600014 cites W2117317462 @default.
- W2203600014 cites W2168234252 @default.
- W2203600014 cites W2231812784 @default.
- W2203600014 cites W2277929089 @default.
- W2203600014 cites W2314053362 @default.
- W2203600014 cites W2418359589 @default.
- W2203600014 cites W2474676624 @default.
- W2203600014 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1886752" @default.
- W2203600014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1466405" @default.
- W2203600014 hasPublicationYear "1992" @default.
- W2203600014 type Work @default.
- W2203600014 sameAs 2203600014 @default.
- W2203600014 citedByCount "3" @default.
- W2203600014 countsByYear W22036000142017 @default.
- W2203600014 countsByYear W22036000142021 @default.
- W2203600014 crossrefType "journal-article" @default.
- W2203600014 hasAuthorship W2203600014A5033043946 @default.
- W2203600014 hasAuthorship W2203600014A5052687060 @default.
- W2203600014 hasAuthorship W2203600014A5066024242 @default.
- W2203600014 hasAuthorship W2203600014A5085890251 @default.
- W2203600014 hasAuthorship W2203600014A5089038480 @default.
- W2203600014 hasConcept C126322002 @default.
- W2203600014 hasConcept C126894567 @default.
- W2203600014 hasConcept C134018914 @default.
- W2203600014 hasConcept C142724271 @default.
- W2203600014 hasConcept C2776115139 @default.
- W2203600014 hasConcept C2776193487 @default.
- W2203600014 hasConcept C2777390665 @default.
- W2203600014 hasConcept C2779561371 @default.
- W2203600014 hasConcept C2780091579 @default.
- W2203600014 hasConcept C2780227381 @default.
- W2203600014 hasConcept C2909276006 @default.
- W2203600014 hasConcept C3060791 @default.
- W2203600014 hasConcept C71924100 @default.
- W2203600014 hasConceptScore W2203600014C126322002 @default.
- W2203600014 hasConceptScore W2203600014C126894567 @default.
- W2203600014 hasConceptScore W2203600014C134018914 @default.
- W2203600014 hasConceptScore W2203600014C142724271 @default.
- W2203600014 hasConceptScore W2203600014C2776115139 @default.
- W2203600014 hasConceptScore W2203600014C2776193487 @default.
- W2203600014 hasConceptScore W2203600014C2777390665 @default.
- W2203600014 hasConceptScore W2203600014C2779561371 @default.
- W2203600014 hasConceptScore W2203600014C2780091579 @default.
- W2203600014 hasConceptScore W2203600014C2780227381 @default.
- W2203600014 hasConceptScore W2203600014C2909276006 @default.
- W2203600014 hasConceptScore W2203600014C3060791 @default.
- W2203600014 hasConceptScore W2203600014C71924100 @default.
- W2203600014 hasIssue "6" @default.
- W2203600014 hasLocation W22036000141 @default.
- W2203600014 hasOpenAccess W2203600014 @default.
- W2203600014 hasPrimaryLocation W22036000141 @default.
- W2203600014 hasRelatedWork W1968292557 @default.
- W2203600014 hasRelatedWork W1978330386 @default.
- W2203600014 hasRelatedWork W1985257471 @default.
- W2203600014 hasRelatedWork W2025246326 @default.
- W2203600014 hasRelatedWork W2153399138 @default.
- W2203600014 hasRelatedWork W2203600014 @default.
- W2203600014 hasRelatedWork W233082938 @default.
- W2203600014 hasRelatedWork W2363496730 @default.
- W2203600014 hasRelatedWork W2400530676 @default.
- W2203600014 hasRelatedWork W2175017023 @default.
- W2203600014 hasVolume "141" @default.
- W2203600014 isParatext "false" @default.
- W2203600014 isRetracted "false" @default.
- W2203600014 magId "2203600014" @default.
- W2203600014 workType "article" @default.