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• W2203884901 startingPage "855" @default.
• W2203884901 abstract "Serrate and Delta encode structurally related proteins in D. melanogaster that bind within a common extracellular region on the NOTCH receptor molecule. We used ectopic expression to determine if SERRATE could mediate in vivo functions parallel or antagonistic to those proposed for the putative NOTCH ligand DELTA. Our results demonstrate that Serrate can replace Delta gene function during embryonic neuroblast segregation and that expression of Serrate leads to a NOTCH-dependent suppression of achaete expression in proneural clusters. Our findings strongly suggest that SERRATE functions as an alternative ligand capable of NOTCH activation." @default.
• W2203884901 created "2016-06-24" @default.
• W2203884901 creator A5029364587 @default.
• W2203884901 creator A5038463777 @default.
• W2203884901 creator A5066510848 @default.
• W2203884901 date "1995-03-01" @default.
• W2203884901 modified "2023-10-18" @default.
• W2203884901 title "<i>Serrate</i> expression can functionally replace <i>Delta</i> activity during neuroblast segregation in the <i>Drosophila</i> embryo" @default.
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• W2203884901 doi "https://doi.org/10.1242/dev.121.3.855" @default.
• W2203884901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7720588" @default.
• W2203884901 hasPublicationYear "1995" @default.
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