FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2204114105> ?p ?o ?g. }

• W2204114105 endingPage "1984" @default.
• W2204114105 startingPage "1976" @default.
• W2204114105 abstract "A working example of relative solvent accessibility (RSA) prediction for proteins is presented. Novel logistic regression models with various qualitative descriptors that include amino acid type and quantitative descriptors that include 20- and six-term sequence entropy have been built and validated. A domain-complete learning set of over 1300 proteins is used to fit initial models with various sequence homology descriptors as well as query residue qualitative descriptors. Homology descriptors are derived from BLASTp sequence alignments, whereas the RSA values are determined directly from the crystal structure. The logistic regression models are fitted using dichotomous responses indicating buried or accessible solvent, with binary classifications obtained from the RSA values. The fitted models determine binary predictions of residue solvent accessibility with accuracies comparable to other less computationally intensive methods using the standard RSA threshold criteria 20 and 25% as solvent accessible. When an additional non-homology descriptor describing Lobanov-Galzitskaya residue disorder propensity is included, incremental improvements in accuracy are achieved with 25% threshold accuracies of 76.12 and 74.79% for the Manesh-215 and CASP(8+9) test sets, respectively. Moreover, the described software and the accompanying learning and validation sets allow students and researchers to explore the utility of RSA prediction with simple, physically intuitive models in any number of related applications." @default.
• W2204114105 created "2016-06-24" @default.
• W2204114105 creator A5004471381 @default.
• W2204114105 creator A5008098877 @default.
• W2204114105 creator A5011018782 @default.
• W2204114105 creator A5014084212 @default.
• W2204114105 creator A5017410976 @default.
• W2204114105 creator A5026288607 @default.
• W2204114105 creator A5031238725 @default.
• W2204114105 creator A5052746230 @default.
• W2204114105 creator A5055029174 @default.
• W2204114105 creator A5056695295 @default.
• W2204114105 date "2015-11-10" @default.
• W2204114105 modified "2023-09-27" @default.
• W2204114105 title "Logistic regression models to predict solvent accessible residues using sequence- and homology-based qualitative and quantitative descriptors applied to a domain-complete X-ray structure learning set" @default.
• W2204114105 cites W1747519124 @default.
• W2204114105 cites W1964062873 @default.
• W2204114105 cites W1964880253 @default.
• W2204114105 cites W1967408543 @default.
• W2204114105 cites W1976005460 @default.
• W2204114105 cites W1976521702 @default.
• W2204114105 cites W1984748839 @default.
• W2204114105 cites W1994983243 @default.
• W2204114105 cites W2003996804 @default.
• W2204114105 cites W2004360551 @default.
• W2204114105 cites W2008708467 @default.
• W2204114105 cites W2021904716 @default.
• W2204114105 cites W2036634847 @default.
• W2204114105 cites W2039248602 @default.
• W2204114105 cites W2043199972 @default.
• W2204114105 cites W2050625197 @default.
• W2204114105 cites W2054453390 @default.
• W2204114105 cites W2057289558 @default.
• W2204114105 cites W2058017150 @default.
• W2204114105 cites W2059168883 @default.
• W2204114105 cites W2071834506 @default.
• W2204114105 cites W2076052898 @default.
• W2204114105 cites W2078022354 @default.
• W2204114105 cites W2091243866 @default.
• W2204114105 cites W2091565674 @default.
• W2204114105 cites W2099779794 @default.
• W2204114105 cites W2100070946 @default.
• W2204114105 cites W2103210604 @default.
• W2204114105 cites W2108862316 @default.
• W2204114105 cites W2109300715 @default.
• W2204114105 cites W2110336366 @default.
• W2204114105 cites W2111705855 @default.
• W2204114105 cites W2111909811 @default.
• W2204114105 cites W2116743097 @default.
• W2204114105 cites W2117121871 @default.
• W2204114105 cites W2117519369 @default.
• W2204114105 cites W2120744225 @default.
• W2204114105 cites W2123957843 @default.
• W2204114105 cites W2132926880 @default.
• W2204114105 cites W2133076404 @default.
• W2204114105 cites W2134141065 @default.
• W2204114105 cites W2137415168 @default.
• W2204114105 cites W2141624700 @default.
• W2204114105 cites W2141627929 @default.
• W2204114105 cites W2143210482 @default.
• W2204114105 cites W2150346640 @default.
• W2204114105 cites W2153153865 @default.
• W2204114105 cites W2158714788 @default.
• W2204114105 cites W2174043882 @default.
• W2204114105 doi "https://doi.org/10.1107/s1600576715018531" @default.
• W2204114105 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4665666" @default.
• W2204114105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26664348" @default.
• W2204114105 hasPublicationYear "2015" @default.
• W2204114105 type Work @default.
• W2204114105 sameAs 2204114105 @default.
• W2204114105 citedByCount "4" @default.
• W2204114105 countsByYear W22041141052018 @default.
• W2204114105 countsByYear W22041141052019 @default.
• W2204114105 countsByYear W22041141052022 @default.
• W2204114105 crossrefType "journal-article" @default.
• W2204114105 hasAuthorship W2204114105A5004471381 @default.
• W2204114105 hasAuthorship W2204114105A5008098877 @default.
• W2204114105 hasAuthorship W2204114105A5011018782 @default.
• W2204114105 hasAuthorship W2204114105A5014084212 @default.
• W2204114105 hasAuthorship W2204114105A5017410976 @default.
• W2204114105 hasAuthorship W2204114105A5026288607 @default.
• W2204114105 hasAuthorship W2204114105A5031238725 @default.
• W2204114105 hasAuthorship W2204114105A5052746230 @default.
• W2204114105 hasAuthorship W2204114105A5055029174 @default.
• W2204114105 hasAuthorship W2204114105A5056695295 @default.
• W2204114105 hasBestOaLocation W22041141051 @default.
• W2204114105 hasConcept C105795698 @default.
• W2204114105 hasConcept C124101348 @default.
• W2204114105 hasConcept C151956035 @default.
• W2204114105 hasConcept C153180895 @default.
• W2204114105 hasConcept C154945302 @default.
• W2204114105 hasConcept C169627665 @default.
• W2204114105 hasConcept C18051474 @default.
• W2204114105 hasConcept C181199279 @default.
• W2204114105 hasConcept C185592680 @default.
• W2204114105 hasConcept C33923547 @default.
• W2204114105 hasConcept C41008148 @default.
• W2204114105 hasConcept C47701112 @default.

• next