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- W2204114354 abstract "BackgroundObservational studies have suggested that various nutrients, dietary supplements, and vitamins may delay the onset of age-associated cognitive decline and dementia. We systematically reviewed recent randomized controlled trials investigating the effect of nutritional interventions on cognitive performance in older non-demented adults.MethodsWe searched MEDLINE, CINAHL, Embase, and the Cochrane Library for articles published between 2003 and 2013. We included randomized trials of ≥ 3 months’ duration that examined the cognitive effects of a nutritional intervention in non-demented adults > 40 years of age. Meta-analyses were done when sufficient trials were available.ResultsTwenty-four trials met inclusion criteria (six omega-3 fatty acids, seven B vitamins, three vitamin E, eight other interventions). In the meta-analyses, omega-3 fatty acids showed no significant effect on Mini-Mental State Examination (MMSE) scores (four trials, mean difference 0.06, 95% CI -0.08 – 0.19) or digit span forward (three trials, mean difference -0.02, 95% CI -0.30 – 0.25), while B vitamins showed no significant effect on MMSE scores (three trials, mean difference 0.02, 95% CI -0.22 – 0.25). None of the vitamin E studies reported significant effects on cognitive outcomes. Among the other nutritional interventions, statistically significant differences between the intervention and control groups on at least one cognitive domain were found in single studies of green tea extract, Concord grape juice, chromium picolinate, betacarotene, two different combinations of multiple vitamins, and a dietary approach developed for the control of hypertension.ConclusionsOmega-3 fatty acids, B vitamins, and vitamin E supplementation did not affect cognition in non-demented middle-aged and older adults. Other nutritional interventions require further evaluation before their use can be advocated for the prevention of age-associated cognitive decline and dementia." @default.
- W2204114354 created "2016-06-24" @default.
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- W2204114354 creator A5066292717 @default.
- W2204114354 creator A5080815644 @default.
- W2204114354 creator A5088618470 @default.
- W2204114354 date "2015-10-16" @default.
- W2204114354 modified "2023-10-18" @default.
- W2204114354 title "Effect of Nutrients, Dietary Supplements and Vitamins on Cognition: a Systematic Review and Meta-Analysis of Randomized Controlled Trials" @default.
- W2204114354 cites W1512343954 @default.
- W2204114354 cites W1531103650 @default.
- W2204114354 cites W1540790109 @default.
- W2204114354 cites W1564984658 @default.
- W2204114354 cites W1762583610 @default.
- W2204114354 cites W1837131274 @default.
- W2204114354 cites W1856821846 @default.
- W2204114354 cites W1919272385 @default.
- W2204114354 cites W1945836171 @default.
- W2204114354 cites W1948763420 @default.
- W2204114354 cites W1953523985 @default.
- W2204114354 cites W1962552915 @default.
- W2204114354 cites W1968083875 @default.
- W2204114354 cites W1968245261 @default.
- W2204114354 cites W1971654647 @default.
- W2204114354 cites W1977104428 @default.
- W2204114354 cites W1986833517 @default.
- W2204114354 cites W1990559218 @default.
- W2204114354 cites W2010205820 @default.
- W2204114354 cites W2013097029 @default.
- W2204114354 cites W2013204019 @default.
- W2204114354 cites W2015640894 @default.
- W2204114354 cites W2019523275 @default.
- W2204114354 cites W2032389768 @default.
- W2204114354 cites W2032660040 @default.
- W2204114354 cites W2032698104 @default.
- W2204114354 cites W2034960280 @default.
- W2204114354 cites W2050438584 @default.
- W2204114354 cites W2051767095 @default.
- W2204114354 cites W2052534047 @default.
- W2204114354 cites W2053771014 @default.
- W2204114354 cites W2055821827 @default.
- W2204114354 cites W2057775085 @default.
- W2204114354 cites W2058041678 @default.
- W2204114354 cites W2062595312 @default.
- W2204114354 cites W2065619873 @default.
- W2204114354 cites W2067430522 @default.
- W2204114354 cites W2075373003 @default.
- W2204114354 cites W2086581430 @default.
- W2204114354 cites W2087122305 @default.
- W2204114354 cites W2087443596 @default.
- W2204114354 cites W2091695719 @default.
- W2204114354 cites W2093391499 @default.
- W2204114354 cites W2097664820 @default.
- W2204114354 cites W2097676935 @default.
- W2204114354 cites W2097799979 @default.
- W2204114354 cites W2097980836 @default.
- W2204114354 cites W2102315975 @default.
- W2204114354 cites W2107820540 @default.
- W2204114354 cites W2111572957 @default.
- W2204114354 cites W2115040753 @default.
- W2204114354 cites W2115978010 @default.
- W2204114354 cites W2116201829 @default.
- W2204114354 cites W2116424646 @default.
- W2204114354 cites W2117825326 @default.
- W2204114354 cites W2122522567 @default.
- W2204114354 cites W2124956656 @default.
- W2204114354 cites W2127884053 @default.
- W2204114354 cites W2133052971 @default.
- W2204114354 cites W2133190709 @default.
- W2204114354 cites W2139972696 @default.
- W2204114354 cites W2142751850 @default.
- W2204114354 cites W2143033384 @default.
- W2204114354 cites W2143505009 @default.
- W2204114354 cites W2146361460 @default.
- W2204114354 cites W2147668927 @default.
- W2204114354 cites W2149839645 @default.
- W2204114354 cites W2153415741 @default.
- W2204114354 cites W2156098321 @default.
- W2204114354 cites W2156450532 @default.
- W2204114354 cites W2162124991 @default.
- W2204114354 cites W2167986509 @default.
- W2204114354 cites W2168895330 @default.
- W2204114354 cites W2169530911 @default.
- W2204114354 cites W2169878253 @default.
- W2204114354 cites W2170900258 @default.
- W2204114354 cites W2438827874 @default.
- W2204114354 cites W3211395210 @default.
- W2204114354 doi "https://doi.org/10.5770/cgj.18.189" @default.
- W2204114354 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4696451" @default.
- W2204114354 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26740832" @default.
- W2204114354 hasPublicationYear "2015" @default.
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