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- W2205167788 abstract "In 2007, FTO was identified as the first genome-wide association study (GWAS) gene associated with obesity in humans. Since then, various animal models have served to establish the mechanistic basis behind this association. Many earlier studies focussed on FTO’s effects on food intake via central mechanisms. Emerging evidence, however, implicates adipose tissue development and function in the causal relationship between perturbations in FTO expression and obesity. The purpose of this mini review is to shed light on these new studies of FTO function in adipose tissue and present a clearer picture of its impact on obesity susceptibility." @default.
- W2205167788 created "2016-06-24" @default.
- W2205167788 creator A5009947281 @default.
- W2205167788 creator A5037781683 @default.
- W2205167788 date "2015-01-01" @default.
- W2205167788 modified "2023-09-25" @default.
- W2205167788 title "Role of FTO in Adipocyte Development and Function: Recent Insights" @default.
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- W2205167788 doi "https://doi.org/10.1155/2015/521381" @default.
- W2205167788 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4695642" @default.
- W2205167788 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26788058" @default.
- W2205167788 hasPublicationYear "2015" @default.
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