Matches in SemOpenAlex for { <https://semopenalex.org/work/W2205200295> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2205200295 abstract "Castor oil (2 ml/rat) produced copious diarrhoea in all rats 3 h after challenge, which was associated with histologic damage to the duodenal and jejunal mucosa. Pretreatment of animals with the nitric oxide (NO) synthesis inhibitor N G -nitro-L-arginine methyl ester (L-NAME, 50 mg/kg, i.p.) reverted the diarrhoea, but, exacerbated histological damage. The NO donating compound isosorbide-5-mononitrate (IMN, 150 mg/kg p.o.) counteracted the augmentation by L-NAME of the castor oil-induced diarrhoea and histological damage. The independence of the diarrhoeal and damaging effects of castor oil suggest that NO (i) has protective effects on the rat intestinal mucosa, (ii) mediates laxation and (iii) modulates the release of local cytotoxic substances." @default.
- W2205200295 created "2016-06-24" @default.
- W2205200295 creator A5002541055 @default.
- W2205200295 creator A5003063315 @default.
- W2205200295 creator A5029108253 @default.
- W2205200295 creator A5048888168 @default.
- W2205200295 creator A5051892931 @default.
- W2205200295 date "1996-01-01" @default.
- W2205200295 modified "2023-09-25" @default.
- W2205200295 title "Diarrhoea and Mucosal Injury Evoked by Castor Oil are Independent Events" @default.
- W2205200295 cites W1967600393 @default.
- W2205200295 cites W2017607478 @default.
- W2205200295 cites W2064750587 @default.
- W2205200295 doi "https://doi.org/10.1076/phbi.34.2.91.13198" @default.
- W2205200295 hasPublicationYear "1996" @default.
- W2205200295 type Work @default.
- W2205200295 sameAs 2205200295 @default.
- W2205200295 citedByCount "0" @default.
- W2205200295 crossrefType "journal-article" @default.
- W2205200295 hasAuthorship W2205200295A5002541055 @default.
- W2205200295 hasAuthorship W2205200295A5003063315 @default.
- W2205200295 hasAuthorship W2205200295A5029108253 @default.
- W2205200295 hasAuthorship W2205200295A5048888168 @default.
- W2205200295 hasAuthorship W2205200295A5051892931 @default.
- W2205200295 hasConcept C126322002 @default.
- W2205200295 hasConcept C185592680 @default.
- W2205200295 hasConcept C2778229996 @default.
- W2205200295 hasConcept C2779802037 @default.
- W2205200295 hasConcept C3019368612 @default.
- W2205200295 hasConcept C519581460 @default.
- W2205200295 hasConcept C55493867 @default.
- W2205200295 hasConcept C71924100 @default.
- W2205200295 hasConcept C90924648 @default.
- W2205200295 hasConcept C98274493 @default.
- W2205200295 hasConceptScore W2205200295C126322002 @default.
- W2205200295 hasConceptScore W2205200295C185592680 @default.
- W2205200295 hasConceptScore W2205200295C2778229996 @default.
- W2205200295 hasConceptScore W2205200295C2779802037 @default.
- W2205200295 hasConceptScore W2205200295C3019368612 @default.
- W2205200295 hasConceptScore W2205200295C519581460 @default.
- W2205200295 hasConceptScore W2205200295C55493867 @default.
- W2205200295 hasConceptScore W2205200295C71924100 @default.
- W2205200295 hasConceptScore W2205200295C90924648 @default.
- W2205200295 hasConceptScore W2205200295C98274493 @default.
- W2205200295 hasLocation W22052002951 @default.
- W2205200295 hasOpenAccess W2205200295 @default.
- W2205200295 hasPrimaryLocation W22052002951 @default.
- W2205200295 hasRelatedWork W1506577795 @default.
- W2205200295 hasRelatedWork W1791264693 @default.
- W2205200295 hasRelatedWork W1967368134 @default.
- W2205200295 hasRelatedWork W1982773761 @default.
- W2205200295 hasRelatedWork W1988313806 @default.
- W2205200295 hasRelatedWork W1992356182 @default.
- W2205200295 hasRelatedWork W1994217478 @default.
- W2205200295 hasRelatedWork W1995622225 @default.
- W2205200295 hasRelatedWork W1999554137 @default.
- W2205200295 hasRelatedWork W2015834574 @default.
- W2205200295 hasRelatedWork W2019986382 @default.
- W2205200295 hasRelatedWork W2036164554 @default.
- W2205200295 hasRelatedWork W2052244760 @default.
- W2205200295 hasRelatedWork W2054845878 @default.
- W2205200295 hasRelatedWork W2061229425 @default.
- W2205200295 hasRelatedWork W2093144486 @default.
- W2205200295 hasRelatedWork W2095004780 @default.
- W2205200295 hasRelatedWork W2360349675 @default.
- W2205200295 hasRelatedWork W2436512393 @default.
- W2205200295 hasRelatedWork W69137090 @default.
- W2205200295 isParatext "false" @default.
- W2205200295 isRetracted "false" @default.
- W2205200295 magId "2205200295" @default.
- W2205200295 workType "article" @default.