FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2205517873> ?p ?o ?g. }

• W2205517873 endingPage "323" @default.
• W2205517873 startingPage "313" @default.
• W2205517873 abstract "Activities of phosphatidate phosphohydrolase and palmitoyl-CoA hydrolase were determined in cardiac subcellular fractions prepared from rabbits which has received tri-iodothyronine and from hamsters with hereditary cardiomyopathy (strain BIO 14.6). 1. Both mitochondrial and microsomal fractions of hyperthyroid rabbit hearts produced 4–5 times as much diacylglycerol 3-phosphate from glycerol 3-phosphate and palmitate as did those of euthyroid hearts. 2. Phosphatidate phosphohydrolase, measured with phosphatidate emulsion, was activated by 1mm-Mg2+ in all but the mitochondrial fraction of euthyroid rabbit hearts. The activation was more pronounced in subcellular fractions isolated from hyperthyroid hearts, so that the measured activities were significantly increased above those of the controls. The highest activity was found in the microsomal and lysosomal fractions. 3. In the absence of Mg2+ during incubation, the difference in phosphohydrolase activities between eu- and hyper-thyroid states was not significant. 4. The phosphohydrolase of subcellular fractions of control hamsters did not respond to addition of 0.5–8.0mm-Mg2+. The enzyme from cardiomyopathic hearts was slightly inhibited by this bivalent cation and therefore significant increases in activity were observed only in the absence of Mg2+ from the assay system. 5. The rate of reaction by soluble phosphatidate phosphohydrolase was similar regardless of the nature of the substrate. Both when microsomal-bound phosphatidate was used as the substrate and when phosphatidate suspension was used, the activity of soluble enzyme was lower than that of the microsomal and lysosomal enzymes measured with phosphatidate suspension; this was especially so when the assay was carried out in the absence of Mg2+. Neither tri-iodothyronine nor cardiomyopathy influenced the soluble phosphohydrolase activity in the two species. 6. Neither tri-iodothyronine nor cardiomyopathy significantly changed palmitoyl-CoA hydrolase activities in subcellular fractions. 7. Microsomal diacylglycerol acyltransferase and myocardial triacylglycerol content were also unchanged in the hyperthyroid state." @default.
• W2205517873 created "2016-06-24" @default.
• W2205517873 creator A5041497660 @default.
• W2205517873 creator A5049560590 @default.
• W2205517873 date "1975-11-15" @default.
• W2205517873 modified "2023-09-26" @default.
• W2205517873 title "Phosphatidate phosphohydrolase and palmitoyl-coenzyme A hydrolase in cardiac subcellular fractions of hyperthyroid rabbits and cardiomyopathic hamsters" @default.
• W2205517873 cites W1522901029 @default.
• W2205517873 cites W1526507834 @default.
• W2205517873 cites W1533735300 @default.
• W2205517873 cites W1544944356 @default.
• W2205517873 cites W1554653315 @default.
• W2205517873 cites W1556440714 @default.
• W2205517873 cites W1558883242 @default.
• W2205517873 cites W1775749144 @default.
• W2205517873 cites W1844822384 @default.
• W2205517873 cites W1862213828 @default.
• W2205517873 cites W1897430514 @default.
• W2205517873 cites W1958079586 @default.
• W2205517873 cites W1967037773 @default.
• W2205517873 cites W1969805452 @default.
• W2205517873 cites W1980189277 @default.
• W2205517873 cites W1982866005 @default.
• W2205517873 cites W1992125037 @default.
• W2205517873 cites W1996756680 @default.
• W2205517873 cites W2000860796 @default.
• W2205517873 cites W2002606327 @default.
• W2205517873 cites W2009794585 @default.
• W2205517873 cites W2014197800 @default.
• W2205517873 cites W2014796761 @default.
• W2205517873 cites W2021309018 @default.
• W2205517873 cites W2021963824 @default.
• W2205517873 cites W2025323312 @default.
• W2205517873 cites W2034783197 @default.
• W2205517873 cites W2039781712 @default.
• W2205517873 cites W2042952685 @default.
• W2205517873 cites W2054014705 @default.
• W2205517873 cites W2059336743 @default.
• W2205517873 cites W2059926379 @default.
• W2205517873 cites W2065079376 @default.
• W2205517873 cites W2066040292 @default.
• W2205517873 cites W2067188229 @default.
• W2205517873 cites W2067732955 @default.
• W2205517873 cites W2068808662 @default.
• W2205517873 cites W2072874415 @default.
• W2205517873 cites W2091929573 @default.
• W2205517873 cites W2096854853 @default.
• W2205517873 cites W2102838772 @default.
• W2205517873 cites W2108547497 @default.
• W2205517873 cites W2118415032 @default.
• W2205517873 cites W2125944581 @default.
• W2205517873 cites W2146993786 @default.
• W2205517873 cites W2152311269 @default.
• W2205517873 cites W2162781556 @default.
• W2205517873 cites W2183199399 @default.
• W2205517873 cites W2183470459 @default.
• W2205517873 cites W2279765817 @default.
• W2205517873 cites W2340129429 @default.
• W2205517873 cites W2400268871 @default.
• W2205517873 cites W2402370209 @default.
• W2205517873 cites W2405384186 @default.
• W2205517873 cites W2413749677 @default.
• W2205517873 cites W2418437953 @default.
• W2205517873 cites W2443129672 @default.
• W2205517873 cites W2463780327 @default.
• W2205517873 cites W4240956570 @default.
• W2205517873 cites W4241035996 @default.
• W2205517873 cites W4246778745 @default.
• W2205517873 cites W55091918 @default.
• W2205517873 cites W72677364 @default.
• W2205517873 cites W85131412 @default.
• W2205517873 doi "https://doi.org/10.1042/bj1520313" @default.
• W2205517873 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1172473" @default.
• W2205517873 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/177001" @default.
• W2205517873 hasPublicationYear "1975" @default.
• W2205517873 type Work @default.
• W2205517873 sameAs 2205517873 @default.
• W2205517873 citedByCount "29" @default.
• W2205517873 crossrefType "journal-article" @default.
• W2205517873 hasAuthorship W2205517873A5041497660 @default.
• W2205517873 hasAuthorship W2205517873A5049560590 @default.
• W2205517873 hasBestOaLocation W22055178732 @default.
• W2205517873 hasConcept C126322002 @default.
• W2205517873 hasConcept C134018914 @default.
• W2205517873 hasConcept C181199279 @default.
• W2205517873 hasConcept C185592680 @default.
• W2205517873 hasConcept C195794163 @default.
• W2205517873 hasConcept C2909482567 @default.
• W2205517873 hasConcept C36020004 @default.
• W2205517873 hasConcept C55493867 @default.
• W2205517873 hasConcept C71924100 @default.
• W2205517873 hasConcept C86803240 @default.
• W2205517873 hasConcept C87644729 @default.
• W2205517873 hasConceptScore W2205517873C126322002 @default.
• W2205517873 hasConceptScore W2205517873C134018914 @default.
• W2205517873 hasConceptScore W2205517873C181199279 @default.
• W2205517873 hasConceptScore W2205517873C185592680 @default.
• W2205517873 hasConceptScore W2205517873C195794163 @default.

• next