Matches in SemOpenAlex for { <https://semopenalex.org/work/W2206155187> ?p ?o ?g. }
- W2206155187 endingPage "687" @default.
- W2206155187 startingPage "681" @default.
- W2206155187 abstract "A novel drug carrier based on hydroxypropyl-β-cyclodextrin (HP-β-CD) modified carboxylated graphene oxide (GO-COOH) was designed to incorporate anti-cancer drug paclitaxel (PTX). The formulated nanomedicines were characterized by Fourier transform infrared spectroscopy (FTIR) and atomic force microscopy (AFM). Results showed that PTX can be incorporated into GO-COO-HP-β-CD nanospheres successfully, with an average diameter of about 100 nm. The solubility and stability of PTX-loaded GO-COO-HP-β-CD nanospheres in aqueous media were greatly enhanced compared with the untreated PTX. The results of hemolysis test demonstrated that the drug-loaded nanospheres were qualified with good blood compatibility for intravenous use. In vitro anti-tumor activity was measured and results demonstrated that the incorporation of PTX into the newly developed GO-COO-HP-β-CD carrier could confer significantly improved cytotoxicity to the nanosystem against tumor cells than single application of PTX. GO-COO-HP-β-CD nanospheres may represent a promising formulation platform for a broad range of therapeutic agent, especially those with poor solubility." @default.
- W2206155187 created "2016-06-24" @default.
- W2206155187 creator A5008764192 @default.
- W2206155187 creator A5009058190 @default.
- W2206155187 creator A5047891108 @default.
- W2206155187 creator A5077529500 @default.
- W2206155187 creator A5080733133 @default.
- W2206155187 creator A5089745505 @default.
- W2206155187 creator A5090997669 @default.
- W2206155187 date "2016-04-01" @default.
- W2206155187 modified "2023-10-16" @default.
- W2206155187 title "Hydroxypropyl-β-cyclodextrin–graphene oxide conjugates: Carriers for anti-cancer drugs" @default.
- W2206155187 cites W1966067091 @default.
- W2206155187 cites W1967381871 @default.
- W2206155187 cites W1973583013 @default.
- W2206155187 cites W1976787731 @default.
- W2206155187 cites W1977446424 @default.
- W2206155187 cites W1980419364 @default.
- W2206155187 cites W1981055785 @default.
- W2206155187 cites W1986651021 @default.
- W2206155187 cites W1989037178 @default.
- W2206155187 cites W2001106724 @default.
- W2206155187 cites W2001630481 @default.
- W2206155187 cites W2005033237 @default.
- W2206155187 cites W2012327304 @default.
- W2206155187 cites W2017923866 @default.
- W2206155187 cites W2020337784 @default.
- W2206155187 cites W2021074056 @default.
- W2206155187 cites W2027239085 @default.
- W2206155187 cites W2028509370 @default.
- W2206155187 cites W2031257867 @default.
- W2206155187 cites W2033266198 @default.
- W2206155187 cites W2034288284 @default.
- W2206155187 cites W2037115454 @default.
- W2206155187 cites W2038505512 @default.
- W2206155187 cites W2040242287 @default.
- W2206155187 cites W2040615473 @default.
- W2206155187 cites W2044647958 @default.
- W2206155187 cites W2047082561 @default.
- W2206155187 cites W2048384946 @default.
- W2206155187 cites W2051242024 @default.
- W2206155187 cites W2073360836 @default.
- W2206155187 cites W2078933633 @default.
- W2206155187 cites W2085062440 @default.
- W2206155187 cites W2090640187 @default.
- W2206155187 cites W2105072076 @default.
- W2206155187 cites W2108165319 @default.
- W2206155187 cites W2134858542 @default.
- W2206155187 cites W2139109539 @default.
- W2206155187 cites W2160874267 @default.
- W2206155187 cites W2169909531 @default.
- W2206155187 cites W2317170059 @default.
- W2206155187 cites W2334475713 @default.
- W2206155187 cites W2569116361 @default.
- W2206155187 cites W4206269690 @default.
- W2206155187 cites W4255762755 @default.
- W2206155187 cites W84169915 @default.
- W2206155187 cites W996021695 @default.
- W2206155187 doi "https://doi.org/10.1016/j.msec.2015.12.098" @default.
- W2206155187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26838897" @default.
- W2206155187 hasPublicationYear "2016" @default.
- W2206155187 type Work @default.
- W2206155187 sameAs 2206155187 @default.
- W2206155187 citedByCount "49" @default.
- W2206155187 countsByYear W22061551872016 @default.
- W2206155187 countsByYear W22061551872017 @default.
- W2206155187 countsByYear W22061551872018 @default.
- W2206155187 countsByYear W22061551872019 @default.
- W2206155187 countsByYear W22061551872020 @default.
- W2206155187 countsByYear W22061551872021 @default.
- W2206155187 countsByYear W22061551872022 @default.
- W2206155187 countsByYear W22061551872023 @default.
- W2206155187 crossrefType "journal-article" @default.
- W2206155187 hasAuthorship W2206155187A5008764192 @default.
- W2206155187 hasAuthorship W2206155187A5009058190 @default.
- W2206155187 hasAuthorship W2206155187A5047891108 @default.
- W2206155187 hasAuthorship W2206155187A5077529500 @default.
- W2206155187 hasAuthorship W2206155187A5080733133 @default.
- W2206155187 hasAuthorship W2206155187A5089745505 @default.
- W2206155187 hasAuthorship W2206155187A5090997669 @default.
- W2206155187 hasConcept C109316439 @default.
- W2206155187 hasConcept C121608353 @default.
- W2206155187 hasConcept C126322002 @default.
- W2206155187 hasConcept C127413603 @default.
- W2206155187 hasConcept C134306372 @default.
- W2206155187 hasConcept C13965031 @default.
- W2206155187 hasConcept C155574463 @default.
- W2206155187 hasConcept C160892712 @default.
- W2206155187 hasConcept C171250308 @default.
- W2206155187 hasConcept C178790620 @default.
- W2206155187 hasConcept C184651966 @default.
- W2206155187 hasConcept C185592680 @default.
- W2206155187 hasConcept C192562407 @default.
- W2206155187 hasConcept C197336794 @default.
- W2206155187 hasConcept C202751555 @default.
- W2206155187 hasConcept C203014093 @default.
- W2206155187 hasConcept C21951064 @default.
- W2206155187 hasConcept C2777292972 @default.