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- W2206334328 abstract "The 11th Pezcoller Symposium, `Molecular Horizons of Cancer Therapeutics', was held on June 5, 6 and 7, 1999, in Rovereto, Italy. The meeting covered a remarkably diverse number of topics with the objective of integrating diierent ¢elds of cancer therapeutics. Several presentations focused on the development of new technologies for drug discovery and screening, as well as on the identi¢cation of gene determinants to drug action. A session was dedicated to immunological approaches to cancer therapeutics with particular emphasis on the manipulation of T-cell-mediated immune responses in tumor immunotherapy. Many presentations elucidated novel strategies designed to target diverse factors involved in regulation of cell cycle progression and of apoptotic responses, such as signal transduction molecules, transcription factors and components of the ubiquitin pathway. The purpose of this synopsis is to highlight presentations focused on signal transduction pathways that are emerging as more promising points of attack by anti-tumor agents (illustrated in Fig. 1), and on technological breakthroughs that could foster the drug discovery process. 2. The penalties of a life without constraints" @default.
- W2206334328 created "2016-06-24" @default.
- W2206334328 creator A5072563828 @default.
- W2206334328 date "2000-05-01" @default.
- W2206334328 modified "2023-09-25" @default.
- W2206334328 title "Molecular horizons of cancer therapeutics" @default.
- W2206334328 doi "https://doi.org/10.1016/s0304-419x(00)00008-1" @default.
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- W2206334328 hasPublicationYear "2000" @default.
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