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- W2206543279 abstract "Human beings are colonized by abundant and diverse microbial communities, collectively termed the human microbiota. These microbes inhabit niches at sites throughout the body and are an important aide in the fight against infectious disease. They protect the host by acting as a significant barrier against invasion by extrinsic pathogens, many of which have evolved sophisticated mechanisms to outcompete the indigenous microbiota. Conversely, a shift in microbiota composition towards less beneficial species (‘dysbiosis’) may act to initiate or worsen disease by compromising the barrier effect. A dysbiotic microbiota may also influence the potency of pathogenic invaders via the transfer of virulence and antibiotic resistance genes. Understanding the complex communities that share our bodies, and the ways in which they interact with pathogens, are therefore important and emerging research goals, which have the potential to inform clinical practice and generate novel therapeutics." @default.
- W2206543279 created "2016-06-24" @default.
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- W2206543279 date "2015-01-01" @default.
- W2206543279 modified "2023-10-17" @default.
- W2206543279 title "The Human Microbiota and Pathogen Interactions" @default.
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- W2206543279 doi "https://doi.org/10.1016/b978-0-12-397169-2.00019-6" @default.
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