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• W2206691172 startingPage "2418" @default.
• W2206691172 abstract "The copper-catalyzed asymmetric conjugate addition (ACA) of nucleophiles onto polyenic Michael acceptors represents an attractive and powerful methodology for the synthesis of relevant chiral molecules, as it enables in a straightforward manner the sequential generation of two or more stereogenic centers. In the last decade, various chiral copper-based catalysts were evaluated in combination with different nucleophiles and Michael acceptors, and have unambiguously demonstrated their usefulness in the control of the regio- and enantioselectivity of the addition. The aim of this review is to report recent breakthroughs achieved in this challenging field." @default.
• W2206691172 created "2016-06-24" @default.
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• W2206691172 date "2015-12-03" @default.
• W2206691172 modified "2023-10-14" @default.
• W2206691172 title "Copper-catalyzed asymmetric conjugate addition of organometallic reagents to extended Michael acceptors" @default.
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• W2206691172 doi "https://doi.org/10.3762/bjoc.11.263" @default.
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