Matches in SemOpenAlex for { <https://semopenalex.org/work/W2207017804> ?p ?o ?g. }
- W2207017804 endingPage "33" @default.
- W2207017804 startingPage "25" @default.
- W2207017804 abstract "Activity-dependent synaptic plasticity is a fundamental cellular process for learning and memory. While electrophysiological plasticity has been intensively studied, morphological plasticity is less clearly understood. This study investigated the effect of presynaptic stimulation on the morphology of a giant mossy fiber-CA3 pyramidal cell synapse, and found that the mossy fiber bouton altered its morphology with an increase in the number of segments. This activity-dependent alteration in morphology required the activation of glutamate receptors and an increase in postsynaptic calcium concentration. In addition, the intercellular retrograde messengers nitric oxide and arachidonic acid were necessary. Simultaneous recordings demonstrated that the morphological complexity of the presynaptic bouton and the amplitude of excitatory postsynaptic currents were well correlated. Thus, a single mossy fiber synapse has the potential for activity-dependent morphological plasticity at the presynaptic bouton, which may be important for learning and memory." @default.
- W2207017804 created "2016-06-24" @default.
- W2207017804 creator A5037584672 @default.
- W2207017804 creator A5042331400 @default.
- W2207017804 creator A5082030573 @default.
- W2207017804 creator A5086122078 @default.
- W2207017804 date "2016-03-01" @default.
- W2207017804 modified "2023-10-05" @default.
- W2207017804 title "Activity-dependent alteration of the morphology of a hippocampal giant synapse" @default.
- W2207017804 cites W1572640432 @default.
- W2207017804 cites W1642243794 @default.
- W2207017804 cites W1677457722 @default.
- W2207017804 cites W1946004772 @default.
- W2207017804 cites W1961476520 @default.
- W2207017804 cites W1968083340 @default.
- W2207017804 cites W1975333295 @default.
- W2207017804 cites W1976225114 @default.
- W2207017804 cites W1976750232 @default.
- W2207017804 cites W1983553517 @default.
- W2207017804 cites W1989244218 @default.
- W2207017804 cites W1989756472 @default.
- W2207017804 cites W1992594183 @default.
- W2207017804 cites W1996158415 @default.
- W2207017804 cites W1996553105 @default.
- W2207017804 cites W2000097259 @default.
- W2207017804 cites W2000282078 @default.
- W2207017804 cites W2006994969 @default.
- W2207017804 cites W2015986915 @default.
- W2207017804 cites W2016756702 @default.
- W2207017804 cites W2019510839 @default.
- W2207017804 cites W2026717174 @default.
- W2207017804 cites W2028160379 @default.
- W2207017804 cites W2035880314 @default.
- W2207017804 cites W2038915296 @default.
- W2207017804 cites W2050066016 @default.
- W2207017804 cites W2055620557 @default.
- W2207017804 cites W2057286178 @default.
- W2207017804 cites W2060584787 @default.
- W2207017804 cites W2063449449 @default.
- W2207017804 cites W2075957585 @default.
- W2207017804 cites W2080351494 @default.
- W2207017804 cites W2099863332 @default.
- W2207017804 cites W2107023247 @default.
- W2207017804 cites W2119701125 @default.
- W2207017804 cites W2135069583 @default.
- W2207017804 cites W2137087019 @default.
- W2207017804 cites W2143187185 @default.
- W2207017804 cites W2143454033 @default.
- W2207017804 cites W2144489822 @default.
- W2207017804 cites W2145226743 @default.
- W2207017804 cites W2149184122 @default.
- W2207017804 cites W2149375724 @default.
- W2207017804 cites W2162407586 @default.
- W2207017804 doi "https://doi.org/10.1016/j.mcn.2015.12.005" @default.
- W2207017804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26687760" @default.
- W2207017804 hasPublicationYear "2016" @default.
- W2207017804 type Work @default.
- W2207017804 sameAs 2207017804 @default.
- W2207017804 citedByCount "13" @default.
- W2207017804 countsByYear W22070178042017 @default.
- W2207017804 countsByYear W22070178042018 @default.
- W2207017804 countsByYear W22070178042021 @default.
- W2207017804 countsByYear W22070178042022 @default.
- W2207017804 countsByYear W22070178042023 @default.
- W2207017804 crossrefType "journal-article" @default.
- W2207017804 hasAuthorship W2207017804A5037584672 @default.
- W2207017804 hasAuthorship W2207017804A5042331400 @default.
- W2207017804 hasAuthorship W2207017804A5082030573 @default.
- W2207017804 hasAuthorship W2207017804A5086122078 @default.
- W2207017804 hasConcept C112592302 @default.
- W2207017804 hasConcept C127445978 @default.
- W2207017804 hasConcept C169760540 @default.
- W2207017804 hasConcept C170493617 @default.
- W2207017804 hasConcept C17077164 @default.
- W2207017804 hasConcept C194973443 @default.
- W2207017804 hasConcept C197341189 @default.
- W2207017804 hasConcept C25274449 @default.
- W2207017804 hasConcept C26410512 @default.
- W2207017804 hasConcept C55493867 @default.
- W2207017804 hasConcept C61174792 @default.
- W2207017804 hasConcept C86803240 @default.
- W2207017804 hasConcept C98229152 @default.
- W2207017804 hasConceptScore W2207017804C112592302 @default.
- W2207017804 hasConceptScore W2207017804C127445978 @default.
- W2207017804 hasConceptScore W2207017804C169760540 @default.
- W2207017804 hasConceptScore W2207017804C170493617 @default.
- W2207017804 hasConceptScore W2207017804C17077164 @default.
- W2207017804 hasConceptScore W2207017804C194973443 @default.
- W2207017804 hasConceptScore W2207017804C197341189 @default.
- W2207017804 hasConceptScore W2207017804C25274449 @default.
- W2207017804 hasConceptScore W2207017804C26410512 @default.
- W2207017804 hasConceptScore W2207017804C55493867 @default.
- W2207017804 hasConceptScore W2207017804C61174792 @default.
- W2207017804 hasConceptScore W2207017804C86803240 @default.
- W2207017804 hasConceptScore W2207017804C98229152 @default.
- W2207017804 hasLocation W22070178041 @default.
- W2207017804 hasLocation W22070178042 @default.
- W2207017804 hasOpenAccess W2207017804 @default.