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- W2207027312 abstract "4 kinds of Regional Special Natural Products (RSNPs), such as Anthrisci radix, Psoraleae semen, Siegesbeckiae herba and Corni fructus were examined to verify for anti-obesity effect. PPARγ (peroxisome proliferator-activated receptor γ) from 3T3-L1 cell concerning adipocyte differentiation was suppressed by different concentraton of 4 with western blot, when treated RSNPs extract and MDI (IBMX, Dexamethasone, Insulin) at the same time. Also, SREBP-1 (Sterol regulatory element binding protein) controlling lipogenesis and PPARγ expression levels were reduced by these 4 RSNPs extract, when these chemicals after differentiation of 3T3-L1 cell. And lipid droplets were reduced by 7.5%, 14.4%, 18.3% and 30% at different concentration of Anthrisci radix from Oil Red O staining. Also, it was reduced by 2%, 4.9%, 9.3% and 38% at different concentration of Psoraleae semen. For Siegesbeckiae herba, it was inhibited by 1.4%, 6.4%, 16.4% and 30.1%, respectively. And Corni fructus was also showed by 0.9%, 6.3%, 13.7% and 33% at same concentration of Siegesbeckiae herba. These 4 kinds of were expected for a useful material for anti-obesity materials." @default.
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- W2207027312 date "2009-12-01" @default.
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- W2207027312 title "지역 특산 천연산물 전호, 파고지, 희첨 및 산수유의 항비만효과 규명" @default.
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