FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2207253268> ?p ?o ?g. }

• W2207253268 abstract "The economic burden of heart disease is heavy and growing. As advanced technologies for treating heart disease become available, decision makers need to be able to assess the relative value of such options against existing standards of care.To compare the clinical and economic benefits of a percutaneous ventricular assist device (pVAD) versus an intra-aortic balloon pump (IABP) observed during the 90-day duration of the PROTECT II clinical trial, and to supplement these findings with a simulation of the longer-term value of this technology through the use of a Markov model to estimate the incremental cost-effectiveness of a pVAD relative to an IABP, in terms of quality-adjusted life-years (QALYs).Hospital bills were collected for patients enrolled in the PROTECT II trial who received hemodynamic support for high-risk percutaneous coronary intervention (PCI) provided by a pVAD (Impella 2.5) versus a conventional IABP during a 90-day episode of care (EOC). Length of stay, charges, and costs were analyzed for the index admissions, intensive care unit confinements, readmissions, and overall EOC. In addition, a probabilistic Markov model was used to project these parameters and their impact on a patient's quality of life for up to 10 years in relation to a pVAD versus an IABP.Hospital costs for the index admission were lower for the IABP compared with the pVAD ($33,684 vs $47,667; P <.001), whereas readmission length of stay and costs were lower for the pVAD versus the IABP (5 days vs 7 days; and $11,007 vs $21,834, respectively; P <.001). The total 90-day hospital charges were similar for the pVAD and the IABP ($172,564 vs $172,758, respectively; P = .785); however, the total 90-day EOC cost was lower for the IABP than for the pVAD ($44,032 vs $53,171, respectively; P <.001). The median hospital days for the entire EOC were 7 days for the pVAD versus 9 days for the IABP (P = .008). Critical care stays were considerably shorter for a pVAD than for an IABP on readmissions (3.88 days vs 7.00 days; P = .145). Reduction in major adverse cardiovascular and cerebrovascular events resulted in a projected gain of 0.26 QALYs over 10 years, yielding an incremental cost-effectiveness ratio of $39,389/QALY.For high-risk patients with advanced heart failure undergoing PCI, the new pVAD reduced major adverse events, critical care and readmission length of stay, and readmission cost over the 90-day EOC, and was determined to be cost-effective over the long-term. These findings can assist decision makers in forming value-based judgments with regard to new hemodynamic support strategies." @default.
• W2207253268 created "2016-06-24" @default.
• W2207253268 creator A5000112460 @default.
• W2207253268 creator A5009763070 @default.
• W2207253268 creator A5024332733 @default.
• W2207253268 creator A5042287830 @default.
• W2207253268 creator A5045968773 @default.
• W2207253268 creator A5050540625 @default.
• W2207253268 creator A5090230751 @default.
• W2207253268 date "2013-03-01" @default.
• W2207253268 modified "2023-10-11" @default.
• W2207253268 title "A value-based analysis of hemodynamic support strategies for high-risk heart failure patients undergoing a percutaneous coronary intervention." @default.
• W2207253268 cites W156679034 @default.
• W2207253268 cites W1946152282 @default.
• W2207253268 cites W1973275964 @default.
• W2207253268 cites W1978699138 @default.
• W2207253268 cites W2006576252 @default.
• W2207253268 cites W2034406340 @default.
• W2207253268 cites W2034456357 @default.
• W2207253268 cites W2038381502 @default.
• W2207253268 cites W2044064409 @default.
• W2207253268 cites W2050856345 @default.
• W2207253268 cites W2063978051 @default.
• W2207253268 cites W2064357713 @default.
• W2207253268 cites W2073328141 @default.
• W2207253268 cites W2074422015 @default.
• W2207253268 cites W2093002981 @default.
• W2207253268 cites W2103679597 @default.
• W2207253268 cites W2106703370 @default.
• W2207253268 cites W2110579557 @default.
• W2207253268 cites W2116656645 @default.
• W2207253268 cites W2119061468 @default.
• W2207253268 cites W2123748457 @default.
• W2207253268 cites W2127179384 @default.
• W2207253268 cites W2127541834 @default.
• W2207253268 cites W2128323523 @default.
• W2207253268 cites W2130483595 @default.
• W2207253268 cites W2132734525 @default.
• W2207253268 cites W2148046419 @default.
• W2207253268 cites W2150712216 @default.
• W2207253268 cites W2163121576 @default.
• W2207253268 cites W2170131723 @default.
• W2207253268 cites W2171424467 @default.
• W2207253268 cites W2320052487 @default.
• W2207253268 cites W2323060881 @default.
• W2207253268 cites W2585382523 @default.
• W2207253268 cites W2614781785 @default.
• W2207253268 cites W2750358560 @default.
• W2207253268 cites W2760905760 @default.
• W2207253268 cites W178477505 @default.
• W2207253268 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4031707" @default.
• W2207253268 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24991349" @default.
• W2207253268 hasPublicationYear "2013" @default.
• W2207253268 type Work @default.
• W2207253268 sameAs 2207253268 @default.
• W2207253268 citedByCount "3" @default.
• W2207253268 countsByYear W22072532682015 @default.
• W2207253268 countsByYear W22072532682017 @default.
• W2207253268 countsByYear W22072532682022 @default.
• W2207253268 countsByYear W22072532682023 @default.
• W2207253268 crossrefType "journal-article" @default.
• W2207253268 hasAuthorship W2207253268A5000112460 @default.
• W2207253268 hasAuthorship W2207253268A5009763070 @default.
• W2207253268 hasAuthorship W2207253268A5024332733 @default.
• W2207253268 hasAuthorship W2207253268A5042287830 @default.
• W2207253268 hasAuthorship W2207253268A5045968773 @default.
• W2207253268 hasAuthorship W2207253268A5050540625 @default.
• W2207253268 hasAuthorship W2207253268A5090230751 @default.
• W2207253268 hasConcept C126322002 @default.
• W2207253268 hasConcept C164705383 @default.
• W2207253268 hasConcept C177713679 @default.
• W2207253268 hasConcept C194828623 @default.
• W2207253268 hasConcept C2776376669 @default.
• W2207253268 hasConcept C2776850375 @default.
• W2207253268 hasConcept C2778198053 @default.
• W2207253268 hasConcept C2778223703 @default.
• W2207253268 hasConcept C2778774980 @default.
• W2207253268 hasConcept C2780400711 @default.
• W2207253268 hasConcept C2780574415 @default.
• W2207253268 hasConcept C2909476417 @default.
• W2207253268 hasConcept C44249647 @default.
• W2207253268 hasConcept C45393284 @default.
• W2207253268 hasConcept C500558357 @default.
• W2207253268 hasConcept C71924100 @default.
• W2207253268 hasConcept C82789193 @default.
• W2207253268 hasConceptScore W2207253268C126322002 @default.
• W2207253268 hasConceptScore W2207253268C164705383 @default.
• W2207253268 hasConceptScore W2207253268C177713679 @default.
• W2207253268 hasConceptScore W2207253268C194828623 @default.
• W2207253268 hasConceptScore W2207253268C2776376669 @default.
• W2207253268 hasConceptScore W2207253268C2776850375 @default.
• W2207253268 hasConceptScore W2207253268C2778198053 @default.
• W2207253268 hasConceptScore W2207253268C2778223703 @default.
• W2207253268 hasConceptScore W2207253268C2778774980 @default.
• W2207253268 hasConceptScore W2207253268C2780400711 @default.
• W2207253268 hasConceptScore W2207253268C2780574415 @default.
• W2207253268 hasConceptScore W2207253268C2909476417 @default.
• W2207253268 hasConceptScore W2207253268C44249647 @default.
• W2207253268 hasConceptScore W2207253268C45393284 @default.
• W2207253268 hasConceptScore W2207253268C500558357 @default.

• next