Matches in SemOpenAlex for { <https://semopenalex.org/work/W2207422991> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2207422991 endingPage "703" @default.
- W2207422991 startingPage "698" @default.
- W2207422991 abstract "In practices, some cases of salivary basal cell tumors that consist mainly of cribriform growth pattern are difficult to differentiate from adenoid cystic carcinoma (AdCC). Identification of reliable molecular biomarkers for the differential diagnosis between them is required.Twenty-two cases of cribriform salivary basal cell tumors (at least 10% cribriform pattern present in each tumor) comprising 18 cases of basal cell adenoma (BCA) and four cases of basal cell adenocarcinoma (BcAC) were collected between 1985 and 2008. Twenty cases of cribriform AdCC were retrieved from our archives. MYB protein expression and gene abnormalities were detected in all cases by immunohistochemistry (IHC) and fluorescent in situ hybridization (FISH) analyses, respectively.Neither MYB protein nor split genes were detected in any of the cases of cribriform basal cell tumors, while 55% (11/20) of cases of cribriform AdCC had MYB protein expression. High MYB expression was detected in 81.8% (9/11) cases, while low expression was found in the remaining cases. FISH analysis indicated that nine AdCC tumors with high MYB protein expression were split gene-positive, while MYB gene splitting was not detected in the 11 cases with low or absent MYB protein expression.The molecular changes in AdCC differ from those associated with cribriform basal cell tumors, which further confirms that cribriform basal cell tumors and AdCC are two distinct tumor entities. Simultaneous detection of MYB protein expression and the associated molecular changes could be beneficial in differentiating salivary cribriform basal cell tumors from AdCC." @default.
- W2207422991 created "2016-06-24" @default.
- W2207422991 creator A5009689461 @default.
- W2207422991 creator A5009710024 @default.
- W2207422991 creator A5015636491 @default.
- W2207422991 creator A5064492117 @default.
- W2207422991 creator A5070973041 @default.
- W2207422991 date "2015-12-29" @default.
- W2207422991 modified "2023-09-27" @default.
- W2207422991 title "Differences in MYB expression and gene abnormalities further confirm that salivary cribriform basal cell tumors and adenoid cystic carcinoma are two distinct tumor entities" @default.
- W2207422991 cites W1559985792 @default.
- W2207422991 cites W1908454987 @default.
- W2207422991 cites W1929404069 @default.
- W2207422991 cites W1964297775 @default.
- W2207422991 cites W1974202442 @default.
- W2207422991 cites W2007625022 @default.
- W2207422991 cites W2022325658 @default.
- W2207422991 cites W2041921202 @default.
- W2207422991 cites W2048105337 @default.
- W2207422991 cites W2058920288 @default.
- W2207422991 cites W2091194388 @default.
- W2207422991 cites W2104475595 @default.
- W2207422991 cites W2112487172 @default.
- W2207422991 cites W2127209230 @default.
- W2207422991 cites W2141065236 @default.
- W2207422991 doi "https://doi.org/10.1111/jop.12414" @default.
- W2207422991 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26711587" @default.
- W2207422991 hasPublicationYear "2015" @default.
- W2207422991 type Work @default.
- W2207422991 sameAs 2207422991 @default.
- W2207422991 citedByCount "8" @default.
- W2207422991 countsByYear W22074229912016 @default.
- W2207422991 countsByYear W22074229912019 @default.
- W2207422991 countsByYear W22074229912020 @default.
- W2207422991 countsByYear W22074229912021 @default.
- W2207422991 countsByYear W22074229912023 @default.
- W2207422991 crossrefType "journal-article" @default.
- W2207422991 hasAuthorship W2207422991A5009689461 @default.
- W2207422991 hasAuthorship W2207422991A5009710024 @default.
- W2207422991 hasAuthorship W2207422991A5015636491 @default.
- W2207422991 hasAuthorship W2207422991A5064492117 @default.
- W2207422991 hasAuthorship W2207422991A5070973041 @default.
- W2207422991 hasConcept C104317684 @default.
- W2207422991 hasConcept C142724271 @default.
- W2207422991 hasConcept C150194340 @default.
- W2207422991 hasConcept C204232928 @default.
- W2207422991 hasConcept C2777546739 @default.
- W2207422991 hasConcept C2779231225 @default.
- W2207422991 hasConcept C2781163425 @default.
- W2207422991 hasConcept C2909818935 @default.
- W2207422991 hasConcept C502942594 @default.
- W2207422991 hasConcept C54355233 @default.
- W2207422991 hasConcept C62794011 @default.
- W2207422991 hasConcept C71924100 @default.
- W2207422991 hasConcept C86803240 @default.
- W2207422991 hasConceptScore W2207422991C104317684 @default.
- W2207422991 hasConceptScore W2207422991C142724271 @default.
- W2207422991 hasConceptScore W2207422991C150194340 @default.
- W2207422991 hasConceptScore W2207422991C204232928 @default.
- W2207422991 hasConceptScore W2207422991C2777546739 @default.
- W2207422991 hasConceptScore W2207422991C2779231225 @default.
- W2207422991 hasConceptScore W2207422991C2781163425 @default.
- W2207422991 hasConceptScore W2207422991C2909818935 @default.
- W2207422991 hasConceptScore W2207422991C502942594 @default.
- W2207422991 hasConceptScore W2207422991C54355233 @default.
- W2207422991 hasConceptScore W2207422991C62794011 @default.
- W2207422991 hasConceptScore W2207422991C71924100 @default.
- W2207422991 hasConceptScore W2207422991C86803240 @default.
- W2207422991 hasFunder F4320324283 @default.
- W2207422991 hasIssue "9" @default.
- W2207422991 hasLocation W22074229911 @default.
- W2207422991 hasLocation W22074229912 @default.
- W2207422991 hasOpenAccess W2207422991 @default.
- W2207422991 hasPrimaryLocation W22074229911 @default.
- W2207422991 hasRelatedWork W174831240 @default.
- W2207422991 hasRelatedWork W1979199368 @default.
- W2207422991 hasRelatedWork W1982542932 @default.
- W2207422991 hasRelatedWork W2013199356 @default.
- W2207422991 hasRelatedWork W2020681358 @default.
- W2207422991 hasRelatedWork W2031809670 @default.
- W2207422991 hasRelatedWork W2075169442 @default.
- W2207422991 hasRelatedWork W2086495532 @default.
- W2207422991 hasRelatedWork W2167275494 @default.
- W2207422991 hasRelatedWork W2313809290 @default.
- W2207422991 hasVolume "45" @default.
- W2207422991 isParatext "false" @default.
- W2207422991 isRetracted "false" @default.
- W2207422991 magId "2207422991" @default.
- W2207422991 workType "article" @default.