Matches in SemOpenAlex for { <https://semopenalex.org/work/W2207579504> ?p ?o ?g. }
- W2207579504 endingPage "149" @default.
- W2207579504 startingPage "141" @default.
- W2207579504 abstract "Measles virus (MV) is the causative agent of subacute sclerosing panencephalitis (SSPE). We previously reported that the F gene of the SSPE Osaka-2 strain is the major determinant of MV neurovirulence. Because the sites and extents of mutations differ among SSPE strains, it is necessary to determine the mutations responsible for the SSPE-specific phenotypes of individual viral strain. In this study, recombinant viruses containing the envelope-associated genes from the SSPE Osaka-1 strain were generated in the IC323 wild-type MV background. Hamsters inoculated with MV containing the H gene of the Osaka-1 strain displayed hyperactivity and seizures, but usually recovered and survived. Hamsters inoculated with MV containing the F gene of the Osaka-1 strain displayed severe neurologic signs and died. Amino acid substitutions in the heptad repeat A and C regions of the F protein, including a methionine-to-valine substitution at amino acid 94, play major roles in neurovirulence." @default.
- W2207579504 created "2016-06-24" @default.
- W2207579504 creator A5002722938 @default.
- W2207579504 creator A5003214268 @default.
- W2207579504 creator A5030098209 @default.
- W2207579504 creator A5032312057 @default.
- W2207579504 creator A5035550385 @default.
- W2207579504 creator A5046464328 @default.
- W2207579504 creator A5053496525 @default.
- W2207579504 creator A5078437261 @default.
- W2207579504 date "2016-01-01" @default.
- W2207579504 modified "2023-09-24" @default.
- W2207579504 title "Amino acid substitutions in the heptad repeat A and C regions of the F protein responsible for neurovirulence of measles virus Osaka-1 strain from a patient with subacute sclerosing panencephalitis" @default.
- W2207579504 cites W1488708772 @default.
- W2207579504 cites W1554426889 @default.
- W2207579504 cites W1558826439 @default.
- W2207579504 cites W1591890160 @default.
- W2207579504 cites W1605220975 @default.
- W2207579504 cites W1972759043 @default.
- W2207579504 cites W1972940026 @default.
- W2207579504 cites W1976525356 @default.
- W2207579504 cites W1991093481 @default.
- W2207579504 cites W2001949677 @default.
- W2207579504 cites W2010858307 @default.
- W2207579504 cites W2027824183 @default.
- W2207579504 cites W2034227445 @default.
- W2207579504 cites W2039635444 @default.
- W2207579504 cites W2040352410 @default.
- W2207579504 cites W2046907963 @default.
- W2207579504 cites W2048240923 @default.
- W2207579504 cites W2049930955 @default.
- W2207579504 cites W2052669421 @default.
- W2207579504 cites W2063539859 @default.
- W2207579504 cites W2066988264 @default.
- W2207579504 cites W2067847775 @default.
- W2207579504 cites W2070198691 @default.
- W2207579504 cites W2070603988 @default.
- W2207579504 cites W2076462632 @default.
- W2207579504 cites W2077821721 @default.
- W2207579504 cites W2082746416 @default.
- W2207579504 cites W2083661586 @default.
- W2207579504 cites W2091782816 @default.
- W2207579504 cites W2094852083 @default.
- W2207579504 cites W2098607290 @default.
- W2207579504 cites W2099939036 @default.
- W2207579504 cites W2102769295 @default.
- W2207579504 cites W2103920010 @default.
- W2207579504 cites W2111625216 @default.
- W2207579504 cites W2116767130 @default.
- W2207579504 cites W2123029312 @default.
- W2207579504 cites W2124600070 @default.
- W2207579504 cites W2134610294 @default.
- W2207579504 cites W2136487762 @default.
- W2207579504 cites W2143312620 @default.
- W2207579504 cites W2154308638 @default.
- W2207579504 cites W2154936313 @default.
- W2207579504 cites W2158965271 @default.
- W2207579504 cites W2160157197 @default.
- W2207579504 cites W76787895 @default.
- W2207579504 doi "https://doi.org/10.1016/j.virol.2015.10.004" @default.
- W2207579504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26524513" @default.
- W2207579504 hasPublicationYear "2016" @default.
- W2207579504 type Work @default.
- W2207579504 sameAs 2207579504 @default.
- W2207579504 citedByCount "11" @default.
- W2207579504 countsByYear W22075795042016 @default.
- W2207579504 countsByYear W22075795042017 @default.
- W2207579504 countsByYear W22075795042019 @default.
- W2207579504 countsByYear W22075795042020 @default.
- W2207579504 countsByYear W22075795042021 @default.
- W2207579504 countsByYear W22075795042022 @default.
- W2207579504 countsByYear W22075795042023 @default.
- W2207579504 crossrefType "journal-article" @default.
- W2207579504 hasAuthorship W2207579504A5002722938 @default.
- W2207579504 hasAuthorship W2207579504A5003214268 @default.
- W2207579504 hasAuthorship W2207579504A5030098209 @default.
- W2207579504 hasAuthorship W2207579504A5032312057 @default.
- W2207579504 hasAuthorship W2207579504A5035550385 @default.
- W2207579504 hasAuthorship W2207579504A5046464328 @default.
- W2207579504 hasAuthorship W2207579504A5053496525 @default.
- W2207579504 hasAuthorship W2207579504A5078437261 @default.
- W2207579504 hasBestOaLocation W22075795041 @default.
- W2207579504 hasConcept C104317684 @default.
- W2207579504 hasConcept C105702510 @default.
- W2207579504 hasConcept C122146531 @default.
- W2207579504 hasConcept C159047783 @default.
- W2207579504 hasConcept C167625842 @default.
- W2207579504 hasConcept C22070199 @default.
- W2207579504 hasConcept C2522874641 @default.
- W2207579504 hasConcept C2776264772 @default.
- W2207579504 hasConcept C2776438120 @default.
- W2207579504 hasConcept C2778022156 @default.
- W2207579504 hasConcept C2778199166 @default.
- W2207579504 hasConcept C2780912031 @default.
- W2207579504 hasConcept C40767141 @default.
- W2207579504 hasConcept C501734568 @default.
- W2207579504 hasConcept C515207424 @default.
- W2207579504 hasConcept C54355233 @default.