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- W2207688592 abstract "Inhalation of the bacterium Yersinia pestis results in primary pneumonic plague. Pneumonic plague is the most severe manifestation of plague, with mortality rates approaching 100% in the absence of treatment. Its rapid disease progression, lethality, and ability to be transmitted via aerosol have compounded fears of the intentional release of Y. pestis as a biological weapon. Importantly, recent epidemics of plague have highlighted a significant role for pneumonic plague during outbreaks of Y. pestis infections. In this review we describe the characteristics of pneumonic plague, focusing on its disease progression and pathogenesis. The rapid time-course, severity, and difficulty of treating pneumonic plague highlight how differences in the route of disease transmission can enhance the lethality of an already deadly pathogen." @default.
- W2207688592 created "2016-06-24" @default.
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- W2207688592 date "2016-03-01" @default.
- W2207688592 modified "2023-10-10" @default.
- W2207688592 title "Pneumonic Plague: The Darker Side of Yersinia pestis" @default.
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- W2207688592 doi "https://doi.org/10.1016/j.tim.2015.11.008" @default.
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