Matches in SemOpenAlex for { <https://semopenalex.org/work/W2207843962> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2207843962 endingPage "271" @default.
- W2207843962 startingPage "267" @default.
- W2207843962 abstract "Metformin hydrochloride microspheres were prepared by non-aqueous emulsification solvent evaporation method, using hydrophobic polymer i.e. ethyl cellulose and hydroxy propyl methyl cellulose K15M. Spherical microspheres having an entrapment efficiency of 80% -87% and percentage yield of 71% -90% were obtained. The effect of polymer-drug ratio, stirring speed was evaluated with respect to entrapment efficiency 80% -87% and percent yield 71% -90% was obtained. The effect of polymer-drug ratio, stirring speed was evaluated with respect to entrapment efficiency, percentage yield and in vitro drug release behavior. Visual inspection and infrared spectroscopic analysis confirmed the absence of drug-polymer interaction. Te in vitro release profile could be altered significantly by changing the drug to polymers ratio to give sustained release of drug from microspheres. The F2 factor was found to 74% compared with marketed sample. The optimized formulation M8 was kept for stability study at refrigeration temperature, room temperature and at oven temperature (40°C to 45°C) showed no significant drug interaction." @default.
- W2207843962 created "2016-06-24" @default.
- W2207843962 creator A5032102600 @default.
- W2207843962 creator A5043101917 @default.
- W2207843962 creator A5081919182 @default.
- W2207843962 date "2010-03-28" @default.
- W2207843962 modified "2023-09-23" @default.
- W2207843962 title "Formulation and Development of Sustained Release Microspheres of Metformin Hydrochloride" @default.
- W2207843962 hasPublicationYear "2010" @default.
- W2207843962 type Work @default.
- W2207843962 sameAs 2207843962 @default.
- W2207843962 citedByCount "0" @default.
- W2207843962 crossrefType "journal-article" @default.
- W2207843962 hasAuthorship W2207843962A5032102600 @default.
- W2207843962 hasAuthorship W2207843962A5043101917 @default.
- W2207843962 hasAuthorship W2207843962A5081919182 @default.
- W2207843962 hasConcept C127413603 @default.
- W2207843962 hasConcept C134121241 @default.
- W2207843962 hasConcept C141071460 @default.
- W2207843962 hasConcept C159985019 @default.
- W2207843962 hasConcept C178790620 @default.
- W2207843962 hasConcept C185592680 @default.
- W2207843962 hasConcept C189942447 @default.
- W2207843962 hasConcept C192562407 @default.
- W2207843962 hasConcept C2776035855 @default.
- W2207843962 hasConcept C2776174307 @default.
- W2207843962 hasConcept C2776915481 @default.
- W2207843962 hasConcept C2779251873 @default.
- W2207843962 hasConcept C2780471494 @default.
- W2207843962 hasConcept C42360764 @default.
- W2207843962 hasConcept C43617362 @default.
- W2207843962 hasConcept C521977710 @default.
- W2207843962 hasConcept C71924100 @default.
- W2207843962 hasConceptScore W2207843962C127413603 @default.
- W2207843962 hasConceptScore W2207843962C134121241 @default.
- W2207843962 hasConceptScore W2207843962C141071460 @default.
- W2207843962 hasConceptScore W2207843962C159985019 @default.
- W2207843962 hasConceptScore W2207843962C178790620 @default.
- W2207843962 hasConceptScore W2207843962C185592680 @default.
- W2207843962 hasConceptScore W2207843962C189942447 @default.
- W2207843962 hasConceptScore W2207843962C192562407 @default.
- W2207843962 hasConceptScore W2207843962C2776035855 @default.
- W2207843962 hasConceptScore W2207843962C2776174307 @default.
- W2207843962 hasConceptScore W2207843962C2776915481 @default.
- W2207843962 hasConceptScore W2207843962C2779251873 @default.
- W2207843962 hasConceptScore W2207843962C2780471494 @default.
- W2207843962 hasConceptScore W2207843962C42360764 @default.
- W2207843962 hasConceptScore W2207843962C43617362 @default.
- W2207843962 hasConceptScore W2207843962C521977710 @default.
- W2207843962 hasConceptScore W2207843962C71924100 @default.
- W2207843962 hasIssue "1" @default.
- W2207843962 hasLocation W22078439621 @default.
- W2207843962 hasOpenAccess W2207843962 @default.
- W2207843962 hasPrimaryLocation W22078439621 @default.
- W2207843962 hasRelatedWork W1825078979 @default.
- W2207843962 hasRelatedWork W1996913349 @default.
- W2207843962 hasRelatedWork W2002890903 @default.
- W2207843962 hasRelatedWork W2017165797 @default.
- W2207843962 hasRelatedWork W2023455509 @default.
- W2207843962 hasRelatedWork W2036861003 @default.
- W2207843962 hasRelatedWork W2043135871 @default.
- W2207843962 hasRelatedWork W2071687027 @default.
- W2207843962 hasRelatedWork W2087180670 @default.
- W2207843962 hasRelatedWork W2119443885 @default.
- W2207843962 hasRelatedWork W2167202145 @default.
- W2207843962 hasRelatedWork W2229375609 @default.
- W2207843962 hasRelatedWork W2254684047 @default.
- W2207843962 hasRelatedWork W2268100185 @default.
- W2207843962 hasRelatedWork W2269438290 @default.
- W2207843962 hasRelatedWork W2353060268 @default.
- W2207843962 hasRelatedWork W2369044507 @default.
- W2207843962 hasRelatedWork W2464384151 @default.
- W2207843962 hasRelatedWork W2496316631 @default.
- W2207843962 hasRelatedWork W2512101517 @default.
- W2207843962 hasVolume "3" @default.
- W2207843962 isParatext "false" @default.
- W2207843962 isRetracted "false" @default.
- W2207843962 magId "2207843962" @default.
- W2207843962 workType "article" @default.