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- W2208034254 abstract "The aim of this study was to evaluate the prognostic value of lens culinaris 1991utinin-reactive fraction of a-fetoprotein (AFP-L3) in patients with hepatocellular carcinoma (HGG) treated with a combination of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI). Methods: Nineteen patients with HCC whose AFP levels (cutoff value of 10.5 ng/ml) maintained a positive (n=11) or negative (n=8) status during post treatment observation were studied. There was no significant difference between groups in the time between treatment and HCC recurrence (p=O.97), and the cumulative survival rate (p=O.96). AFP-L3 levels were measured by lectin-affinity electrophoresis coupled with antibody-affinity blotting. According to the results of AFP-L3% (AFP-L3/total AFP x 100%) (cutoff value of 10%). the 19 patients were divided into those whose AFP-L3 levels remained or became negative (group 1, n=16), and remained or became positive (group 2, n=3) during the study. Results: Shorter time between treatment and the recurrence of HCC was observed significantly more often in group 2 patients than group 1 (p=O.O4) and overall survival was significantly lower in group 2 patients than group 1 (p=O.O2). Conclusion: Our results suggest that AFP-L3 levels are a prognostic facto r for HCC." @default.
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- W2208034254 date "2004-07-01" @default.
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- W2208034254 title "Lectin-reactive Alpha-fetoprotein (AFP-L3) as a Prognostic Factor in Non-surgical Treatment of Hepatocellular Carcinoma" @default.
- W2208034254 doi "https://doi.org/10.6200/tcmj.2004.1.3.05" @default.
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