Matches in SemOpenAlex for { <https://semopenalex.org/work/W2208049576> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2208049576 abstract "Trastuzumab is a monoclonal antibody that is used in biotherapy of the human breast cancer. We labeled this monoclonal antibody with lutetium-177 and performed the in-vitro quality control tests as the first step in production of a new radiopharmaceutical for the therapy of the human breast cancer. The trastuzumab was labeled with lutetium-177 via DOTA as chelator. The stability in the buffer and in the human blood serum were determined using thin layer chromatography. The immunoreactivity and the toxicity of the complex were tested on MCF7 breast cancer cell line. The stability in phosphate buffer and in human blood serum at 96 hrs post preparation were 93%±1.2% and %85±3.5% respectively. The immunoreactivity of the complex was %87±%1.5. The complex in concentration of 1 nM killed 80%±03% of the MCF7cells.. The results showed that the new complex could be considered as a new radiopharmaceutical for radioimmunotherapy of the breast cancer." @default.
- W2208049576 created "2016-06-24" @default.
- W2208049576 creator A5000450348 @default.
- W2208049576 creator A5000893223 @default.
- W2208049576 creator A5006368606 @default.
- W2208049576 creator A5011176951 @default.
- W2208049576 creator A5027084287 @default.
- W2208049576 creator A5038619075 @default.
- W2208049576 creator A5048826303 @default.
- W2208049576 creator A5051305211 @default.
- W2208049576 creator A5054996078 @default.
- W2208049576 creator A5060653118 @default.
- W2208049576 creator A5091747526 @default.
- W2208049576 date "2009-01-01" @default.
- W2208049576 modified "2023-09-26" @default.
- W2208049576 title "The evaluation of therapeutic effect of trastuzumab labeled 177lu in breast cancer cell line" @default.
- W2208049576 doi "https://doi.org/10.1007/978-3-642-03474-9_262" @default.
- W2208049576 hasPublicationYear "2009" @default.
- W2208049576 type Work @default.
- W2208049576 sameAs 2208049576 @default.
- W2208049576 citedByCount "0" @default.
- W2208049576 crossrefType "book-chapter" @default.
- W2208049576 hasAuthorship W2208049576A5000450348 @default.
- W2208049576 hasAuthorship W2208049576A5000893223 @default.
- W2208049576 hasAuthorship W2208049576A5006368606 @default.
- W2208049576 hasAuthorship W2208049576A5011176951 @default.
- W2208049576 hasAuthorship W2208049576A5027084287 @default.
- W2208049576 hasAuthorship W2208049576A5038619075 @default.
- W2208049576 hasAuthorship W2208049576A5048826303 @default.
- W2208049576 hasAuthorship W2208049576A5051305211 @default.
- W2208049576 hasAuthorship W2208049576A5054996078 @default.
- W2208049576 hasAuthorship W2208049576A5060653118 @default.
- W2208049576 hasAuthorship W2208049576A5091747526 @default.
- W2208049576 hasConcept C121608353 @default.
- W2208049576 hasConcept C126322002 @default.
- W2208049576 hasConcept C159654299 @default.
- W2208049576 hasConcept C163864487 @default.
- W2208049576 hasConcept C185592680 @default.
- W2208049576 hasConcept C203014093 @default.
- W2208049576 hasConcept C2775930923 @default.
- W2208049576 hasConcept C2776146153 @default.
- W2208049576 hasConcept C2779786085 @default.
- W2208049576 hasConcept C502942594 @default.
- W2208049576 hasConcept C530470458 @default.
- W2208049576 hasConcept C542903549 @default.
- W2208049576 hasConcept C71924100 @default.
- W2208049576 hasConcept C98274493 @default.
- W2208049576 hasConceptScore W2208049576C121608353 @default.
- W2208049576 hasConceptScore W2208049576C126322002 @default.
- W2208049576 hasConceptScore W2208049576C159654299 @default.
- W2208049576 hasConceptScore W2208049576C163864487 @default.
- W2208049576 hasConceptScore W2208049576C185592680 @default.
- W2208049576 hasConceptScore W2208049576C203014093 @default.
- W2208049576 hasConceptScore W2208049576C2775930923 @default.
- W2208049576 hasConceptScore W2208049576C2776146153 @default.
- W2208049576 hasConceptScore W2208049576C2779786085 @default.
- W2208049576 hasConceptScore W2208049576C502942594 @default.
- W2208049576 hasConceptScore W2208049576C530470458 @default.
- W2208049576 hasConceptScore W2208049576C542903549 @default.
- W2208049576 hasConceptScore W2208049576C71924100 @default.
- W2208049576 hasConceptScore W2208049576C98274493 @default.
- W2208049576 hasLocation W22080495761 @default.
- W2208049576 hasOpenAccess W2208049576 @default.
- W2208049576 hasPrimaryLocation W22080495761 @default.
- W2208049576 hasRelatedWork W1918108602 @default.
- W2208049576 hasRelatedWork W1966850721 @default.
- W2208049576 hasRelatedWork W1982322665 @default.
- W2208049576 hasRelatedWork W2019247704 @default.
- W2208049576 hasRelatedWork W2019492358 @default.
- W2208049576 hasRelatedWork W2051196484 @default.
- W2208049576 hasRelatedWork W2078500408 @default.
- W2208049576 hasRelatedWork W2083666292 @default.
- W2208049576 hasRelatedWork W2084687819 @default.
- W2208049576 hasRelatedWork W2125544080 @default.
- W2208049576 hasRelatedWork W2130870133 @default.
- W2208049576 hasRelatedWork W2136583773 @default.
- W2208049576 hasRelatedWork W2169971416 @default.
- W2208049576 hasRelatedWork W2187207546 @default.
- W2208049576 hasRelatedWork W2276874791 @default.
- W2208049576 hasRelatedWork W2559385525 @default.
- W2208049576 hasRelatedWork W2903406687 @default.
- W2208049576 hasRelatedWork W3003538058 @default.
- W2208049576 hasRelatedWork W3099080752 @default.
- W2208049576 hasRelatedWork W958432650 @default.
- W2208049576 isParatext "false" @default.
- W2208049576 isRetracted "false" @default.
- W2208049576 magId "2208049576" @default.
- W2208049576 workType "book-chapter" @default.