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• W2208113695 endingPage "1938" @default.
• W2208113695 startingPage "1927" @default.
• W2208113695 abstract "A small amount of muscimol (1 microl; concentration, 5 microg/microl) was injected into the ventral and dorsal premotor cortex areas (PMv and PMd, respectively) of monkeys, which then were required to perform a visually guided reaching task. For the task, the monkeys were required to reach for a target soon after it was presented on a screen. While performing the task, the monkeys' eyes were covered with left 10 degrees, right 10 degrees, or no wedge prisms, for a block of 50-100 trials. Without the prisms, the monkeys reached the targets accurately. When the prisms were placed, the monkeys initially misreached the targets because the prisms displaced the visual field. Before the muscimol injection, the monkeys adapted to the prisms in 10-20 trials, judging from the horizontal distance between the target location and the point where the monkey touched the screen. After muscimol injection into the PMv, the monkeys lost the ability to readapt and touched the screen closer to the location of the targets as seen through the prisms. This deficit was observed at selective target locations, only when the targets were shifted contralaterally to the injected hemisphere. When muscimol was injected into the PMd, no such deficits were observed. There were no changes in the reaction and movement times induced by muscimol injections in either area. The results suggest that the PMv plays an important role in motor learning, specifically in recalibrating visual and motor coordinates." @default.
• W2208113695 created "2016-06-24" @default.
• W2208113695 creator A5019180255 @default.
• W2208113695 creator A5062402570 @default.
• W2208113695 date "1999-04-01" @default.
• W2208113695 modified "2023-09-23" @default.
• W2208113695 title "Reacquisition Deficits in Prism Adaptation After Muscimol Microinjection Into the Ventral Premotor Cortex of Monkeys" @default.
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• W2208113695 doi "https://doi.org/10.1152/jn.1999.81.4.1927" @default.
• W2208113695 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10200227" @default.
• W2208113695 hasPublicationYear "1999" @default.
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