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- W2208511062 abstract "Identifying biomarkers for autism can improve outcomes for those affected by autism. Engaging the diverse stakeholders in the research process using community-based participatory research (CBPR) can accelerate biomarker discovery into clinical applications. However, there are limited examples of stakeholder involvement in autism research, possibly due to conceptual and practical concerns. We evaluate the applicability of CBPR principles to biomarker discovery in autism and critically review empirical studies adopting these principles.Using a scoping review methodology, we identified and evaluated seven studies using CBPR principles in biomarker discovery.The limited number of studies in biomarker discovery adopting CBPR principles coupled with their methodological limitations suggests that such applications are feasible but challenging. These studies illustrate three CBPR themes: community assessment, setting global priorities, and collaboration in research design. We propose that further research using participatory principles would be useful in accelerating the pace of discovery and the development of clinically meaningful biomarkers. For this goal to be successful we advocate for increased attention to previously identified conceptual and methodological challenges to participatory approaches in health research, including improving scientific rigor and developing long-term partnerships among stakeholders." @default.
- W2208511062 created "2016-06-24" @default.
- W2208511062 creator A5011910615 @default.
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- W2208511062 date "2015-12-01" @default.
- W2208511062 modified "2023-10-08" @default.
- W2208511062 title "At the cross-roads of participatory research and biomarker discovery in autism: the need for empirical data" @default.
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- W2208511062 doi "https://doi.org/10.1186/s12910-015-0082-0" @default.
- W2208511062 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4681135" @default.
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