FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2208566719> ?p ?o ?g. }

• W2208566719 endingPage "587" @default.
• W2208566719 startingPage "579" @default.
• W2208566719 abstract "We have studied the fine structure of adhesion plaques in chicken embryo fibroblasts (CEF) and visualized the localization of vinculin and talin using immunoelectron microscopy on CEF opened by 'wet-cleaving'. This procedure, performed with nitrocellulose on cells grown on electron microscope grids, cleaved the CEF close to the inner face of the ventral membrane or at a slightly higher level through the cytoplasm. In the resulting preparations, adhesion plaques were identified by their localization at the end of microfilament bundles and by their density of vinculin and talin. The plaques showed a substructure of moderately electron-dense parallel bands that were interconnected. Both the parallel bands as well as the interconnecting threads showed a high density of vinculin and talin labels, whereas neither the surrounding membrane cytoskeleton nor the overlaying bundled microfilaments were labeled. In stereomicrographs, we observed no difference between the distances from vinculin or talin label, respectively, to the plasma membrane. In early spreading cells, vinculin and talin were found to be deposited simultaneously in fine radiating streaks that covered rather large parts of the ventral membrane at areas of close contact with the substratum. These streaks, which were initially overlayed by an isotropic cytoskeletal network without filament bundles, were the apparent precursors of later formed adhesion plaques. These observations suggest that there are no separate layers of talin and vinculin, but rather that adhesion plaques consist of a dense network of talin and vinculin. The observations strongly support the model proposed by Bendori et al. (1989), J. Cell Biol. 108, 2383-2393, that was based on the location of vinculin- and talin-binding sites in the vinculin molecule." @default.
• W2208566719 created "2016-06-24" @default.
• W2208566719 creator A5007690732 @default.
• W2208566719 creator A5034193273 @default.
• W2208566719 creator A5088169023 @default.
• W2208566719 date "1991-11-01" @default.
• W2208566719 modified "2023-10-01" @default.
• W2208566719 title "Organization of talin and vinculin in adhesion plaques of wet-cleaved chicken embryo fibroblasts" @default.
• W2208566719 cites W1595096601 @default.
• W2208566719 cites W1595301421 @default.
• W2208566719 cites W1964350332 @default.
• W2208566719 cites W1984897568 @default.
• W2208566719 cites W1991738124 @default.
• W2208566719 cites W1997420640 @default.
• W2208566719 cites W1998238181 @default.
• W2208566719 cites W2002161597 @default.
• W2208566719 cites W2002980966 @default.
• W2208566719 cites W2007377824 @default.
• W2208566719 cites W2017434825 @default.
• W2208566719 cites W2017613167 @default.
• W2208566719 cites W2021752473 @default.
• W2208566719 cites W2022336036 @default.
• W2208566719 cites W2041534105 @default.
• W2208566719 cites W2051012110 @default.
• W2208566719 cites W2056104802 @default.
• W2208566719 cites W2058170261 @default.
• W2208566719 cites W2067616866 @default.
• W2208566719 cites W2076820834 @default.
• W2208566719 cites W2087874792 @default.
• W2208566719 cites W2100300642 @default.
• W2208566719 cites W2100368368 @default.
• W2208566719 cites W2112093320 @default.
• W2208566719 cites W2119807347 @default.
• W2208566719 cites W2128690724 @default.
• W2208566719 cites W2134130125 @default.
• W2208566719 cites W2138426450 @default.
• W2208566719 cites W2155291985 @default.
• W2208566719 cites W2161899461 @default.
• W2208566719 cites W2169947138 @default.
• W2208566719 cites W2171723086 @default.
• W2208566719 cites W2307166328 @default.
• W2208566719 cites W2406825763 @default.
• W2208566719 cites W2410522727 @default.
• W2208566719 doi "https://doi.org/10.1242/jcs.100.3.579" @default.
• W2208566719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1808206" @default.
• W2208566719 hasPublicationYear "1991" @default.
• W2208566719 type Work @default.
• W2208566719 sameAs 2208566719 @default.
• W2208566719 citedByCount "15" @default.
• W2208566719 countsByYear W22085667192012 @default.
• W2208566719 crossrefType "journal-article" @default.
• W2208566719 hasAuthorship W2208566719A5007690732 @default.
• W2208566719 hasAuthorship W2208566719A5034193273 @default.
• W2208566719 hasAuthorship W2208566719A5088169023 @default.
• W2208566719 hasBestOaLocation W22085667191 @default.
• W2208566719 hasConcept C105702510 @default.
• W2208566719 hasConcept C11960822 @default.
• W2208566719 hasConcept C12554922 @default.
• W2208566719 hasConcept C125705527 @default.
• W2208566719 hasConcept C142669718 @default.
• W2208566719 hasConcept C1491633281 @default.
• W2208566719 hasConcept C151166631 @default.
• W2208566719 hasConcept C159985019 @default.
• W2208566719 hasConcept C189040839 @default.
• W2208566719 hasConcept C190062978 @default.
• W2208566719 hasConcept C192562407 @default.
• W2208566719 hasConcept C2777979848 @default.
• W2208566719 hasConcept C55493867 @default.
• W2208566719 hasConcept C84416704 @default.
• W2208566719 hasConcept C85789140 @default.
• W2208566719 hasConcept C86803240 @default.
• W2208566719 hasConcept C95444343 @default.
• W2208566719 hasConceptScore W2208566719C105702510 @default.
• W2208566719 hasConceptScore W2208566719C11960822 @default.
• W2208566719 hasConceptScore W2208566719C12554922 @default.
• W2208566719 hasConceptScore W2208566719C125705527 @default.
• W2208566719 hasConceptScore W2208566719C142669718 @default.
• W2208566719 hasConceptScore W2208566719C1491633281 @default.
• W2208566719 hasConceptScore W2208566719C151166631 @default.
• W2208566719 hasConceptScore W2208566719C159985019 @default.
• W2208566719 hasConceptScore W2208566719C189040839 @default.
• W2208566719 hasConceptScore W2208566719C190062978 @default.
• W2208566719 hasConceptScore W2208566719C192562407 @default.
• W2208566719 hasConceptScore W2208566719C2777979848 @default.
• W2208566719 hasConceptScore W2208566719C55493867 @default.
• W2208566719 hasConceptScore W2208566719C84416704 @default.
• W2208566719 hasConceptScore W2208566719C85789140 @default.
• W2208566719 hasConceptScore W2208566719C86803240 @default.
• W2208566719 hasConceptScore W2208566719C95444343 @default.
• W2208566719 hasIssue "3" @default.
• W2208566719 hasLocation W22085667191 @default.
• W2208566719 hasLocation W22085667192 @default.
• W2208566719 hasOpenAccess W2208566719 @default.
• W2208566719 hasPrimaryLocation W22085667191 @default.
• W2208566719 hasRelatedWork W113776368 @default.
• W2208566719 hasRelatedWork W177970091 @default.
• W2208566719 hasRelatedWork W1968654001 @default.
• W2208566719 hasRelatedWork W1985208976 @default.

• next