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- W2208687027 abstract "Dermatomyositis is a generalized disorder characterized by myositis and typical cutaneous findings. Dermatomyositis is commonly associated with interstitial lung disease. However, spontaneous pneumomediastinum has been reported as a rare complication in dermatomyositis. Herein, we describe a 57-year-old female patient with dermatomyositis who had the complications of spontaneous pneumomediastinum and extended subcutaneous emphysema. The progressive ulcerative skin lesions were accompanied by refractory pneumomediastinum despite relatively high-dose corticosteroids. The ulcerative skin lesions and pneumomediastinum resolved successfully after treatment with oxygenation therapy and corticosteroids in combination with cyclosporine-A. The patient remained well during more than 6 months of outpatient follow-up after discharge. According to previous studies, spontaneous pneumomediastinum is not associated with interstitial lung disease, but with bronchial necrosis. Necrosis of the bronchial wall caused by focal ischemia due to vasculopathy could result in air leakage with resultant pneumomediastinum." @default.
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- W2208687027 date "2011-06-01" @default.
- W2208687027 modified "2023-09-24" @default.
- W2208687027 title "Spontaneous Pneumomediastinum-A Rare Complication in Dermatomyositis" @default.
- W2208687027 doi "https://doi.org/10.29806/tm.201106.0006" @default.
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