Matches in SemOpenAlex for { <https://semopenalex.org/work/W2209040993> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2209040993 abstract "Taking into account the ability of vitamin B6 vitamers (i.e., pyridoxal, pyridoxine, pyridoxamine) to stimulate adrenomedullary catecholamine outflow and biochemical and cardiovascular changes consistent with adrenoceptor stimulation, this study was undertaken in mice to verify the possibility that pyridoxal (PL), the most potent of the B6 vitamers, could enter into an adverse vitamin-drug interaction when coadministered with a cardioactive drug, and that compounds like taurine (TAU) and labetalol (LAB) could be protective. To this end, mice were treated with PL (200 mg/kg) and isoproterenol (ISO 200 mg/kg), with and without a pretreatment with TAU (300 mg/kg), LAB (30 mg/kg), or TAU plus LAB, and monitored for heart rate, electrocardiographic (ECG) and myocardial electrolyte changes. PL plus ISO lowered the LD50 of ISO and magnified the changes in heart rate, ECG and myocardial electrolytes seen with ISO alone. Pretreating rats with TAU or TAU plus LAB attenuated the cardiovascular changes induced by PL plus ISO to a greater extent than LAB alone. The attenuating actions of TAU and LAB probably reflect independent and complementary mechanisms of action." @default.
- W2209040993 created "2016-06-24" @default.
- W2209040993 creator A5023340669 @default.
- W2209040993 creator A5054807463 @default.
- W2209040993 date "2009-01-01" @default.
- W2209040993 modified "2023-09-26" @default.
- W2209040993 title "Attenuating Action of Taurine and Labetalol on Cardiovascular Alterations by Pyridoxal-Isoproterenol, a Vitamin-Drug Interaction with Cardiopathologic Significance" @default.
- W2209040993 cites W116166431 @default.
- W2209040993 cites W1602022990 @default.
- W2209040993 cites W1967682041 @default.
- W2209040993 cites W1972516159 @default.
- W2209040993 cites W2002032627 @default.
- W2209040993 cites W2040753650 @default.
- W2209040993 cites W2043732010 @default.
- W2209040993 cites W2064318993 @default.
- W2209040993 cites W2075917799 @default.
- W2209040993 cites W2136361791 @default.
- W2209040993 cites W2149532020 @default.
- W2209040993 cites W2005972983 @default.
- W2209040993 doi "https://doi.org/10.1007/978-0-387-75681-3_9" @default.
- W2209040993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19239139" @default.
- W2209040993 hasPublicationYear "2009" @default.
- W2209040993 type Work @default.
- W2209040993 sameAs 2209040993 @default.
- W2209040993 citedByCount "1" @default.
- W2209040993 crossrefType "book-chapter" @default.
- W2209040993 hasAuthorship W2209040993A5023340669 @default.
- W2209040993 hasAuthorship W2209040993A5054807463 @default.
- W2209040993 hasConcept C126322002 @default.
- W2209040993 hasConcept C134018914 @default.
- W2209040993 hasConcept C181199279 @default.
- W2209040993 hasConcept C185592680 @default.
- W2209040993 hasConcept C24998067 @default.
- W2209040993 hasConcept C2776514930 @default.
- W2209040993 hasConcept C2776940978 @default.
- W2209040993 hasConcept C2778428028 @default.
- W2209040993 hasConcept C2779701627 @default.
- W2209040993 hasConcept C2780035454 @default.
- W2209040993 hasConcept C2780859938 @default.
- W2209040993 hasConcept C2909243696 @default.
- W2209040993 hasConcept C515207424 @default.
- W2209040993 hasConcept C55493867 @default.
- W2209040993 hasConcept C71924100 @default.
- W2209040993 hasConcept C98274493 @default.
- W2209040993 hasConceptScore W2209040993C126322002 @default.
- W2209040993 hasConceptScore W2209040993C134018914 @default.
- W2209040993 hasConceptScore W2209040993C181199279 @default.
- W2209040993 hasConceptScore W2209040993C185592680 @default.
- W2209040993 hasConceptScore W2209040993C24998067 @default.
- W2209040993 hasConceptScore W2209040993C2776514930 @default.
- W2209040993 hasConceptScore W2209040993C2776940978 @default.
- W2209040993 hasConceptScore W2209040993C2778428028 @default.
- W2209040993 hasConceptScore W2209040993C2779701627 @default.
- W2209040993 hasConceptScore W2209040993C2780035454 @default.
- W2209040993 hasConceptScore W2209040993C2780859938 @default.
- W2209040993 hasConceptScore W2209040993C2909243696 @default.
- W2209040993 hasConceptScore W2209040993C515207424 @default.
- W2209040993 hasConceptScore W2209040993C55493867 @default.
- W2209040993 hasConceptScore W2209040993C71924100 @default.
- W2209040993 hasConceptScore W2209040993C98274493 @default.
- W2209040993 hasLocation W22090409931 @default.
- W2209040993 hasLocation W22090409932 @default.
- W2209040993 hasOpenAccess W2209040993 @default.
- W2209040993 hasPrimaryLocation W22090409931 @default.
- W2209040993 hasRelatedWork W1898385347 @default.
- W2209040993 hasRelatedWork W1907997524 @default.
- W2209040993 hasRelatedWork W2028264813 @default.
- W2209040993 hasRelatedWork W2034925866 @default.
- W2209040993 hasRelatedWork W2055313585 @default.
- W2209040993 hasRelatedWork W2059312633 @default.
- W2209040993 hasRelatedWork W2064935966 @default.
- W2209040993 hasRelatedWork W2068645755 @default.
- W2209040993 hasRelatedWork W2088671688 @default.
- W2209040993 hasRelatedWork W2104400705 @default.
- W2209040993 hasRelatedWork W2126183364 @default.
- W2209040993 hasRelatedWork W2207877068 @default.
- W2209040993 hasRelatedWork W2216205696 @default.
- W2209040993 hasRelatedWork W2266644155 @default.
- W2209040993 hasRelatedWork W2301995959 @default.
- W2209040993 hasRelatedWork W2408903222 @default.
- W2209040993 hasRelatedWork W2411255411 @default.
- W2209040993 hasRelatedWork W2415483480 @default.
- W2209040993 hasRelatedWork W2418161417 @default.
- W2209040993 hasRelatedWork W2418417824 @default.
- W2209040993 isParatext "false" @default.
- W2209040993 isRetracted "false" @default.
- W2209040993 magId "2209040993" @default.
- W2209040993 workType "book-chapter" @default.