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• W2210246735 abstract "Alginate nanocomposite hydrogels with incorporated electrochemically synthesized silver nanoparticles were investigated regarding cytotoxicity in vitro. Direct contact test of Ag/alginate discs was applied in 2D monolayer cultures of bovine calf chondrocytes while a 3D culture of bovine articular cartilage explants pressed by the discs was established in a biomimetic bioreactor with dynamic compression in the physiological regime (10 % strain, 0.84 Hz frequency, 1 h on / 1 h off). Moderate cytotoxicity was observed in 2D cell cultures as opposed to findings in 3D explant cultures, which were not affected by the Ag/alginate discs despite the compression." @default.
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• W2210246735 date "2015-11-01" @default.
• W2210246735 modified "2023-09-30" @default.
• W2210246735 title "Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures" @default.
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• W2210246735 doi "https://doi.org/10.1109/bibe.2015.7367664" @default.
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