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- W221051844 abstract "This chapter discusses hyperbolic or sigmoid activation kinetics by Rb ions at cytoplasmic sites. A striking finding in the studies of Rb–Rb exchange was the fact that in the absence of ATP and Pi, there was a strictly hyperbolic dependence on concentration of Rb at cytoplasmic sites. The passive Rb movements in the vesicles occur in the simplest of transport conditions, and, thus, provide a convenient system for investigating the requirements for the manifestation of a hyperbolic or sigmoid dependence on Rb concentration. The chapter describes the effects of different cations at the trans face and measures the vanadate-inhibitable component of the total Rb uptake. There are two sub-conformations of the pump, one of which displays hyperbolic behavior and the other sigmoid behavior. Sigmoid behavior implies that more than one Rb ion must be bound to the pump protein and transported in each cycle." @default.
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- W221051844 date "1983-01-01" @default.
- W221051844 modified "2023-09-23" @default.
- W221051844 title "INTERCONVERSIONS BETWEEN SUB-CONFORMATIONAL STATES OF THE NA/K PUMP, SHOWING SIGMOID OR HYPERBOLIC ACTIVATION OF RB MOVEMENTS" @default.
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- W221051844 doi "https://doi.org/10.1016/b978-0-444-80540-9.50008-x" @default.
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