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- W2210931143 abstract "Type 2 diabetes mellitus (T2DM) involves many organ systems and is associated with a wide range of neurologic complications. However, it is not known whether T2DM is a risk factor of hydrocephalus. Research data were retrieved from the National Health Insurance Research Database of Taiwan. A total of 25,903 individuals with T2DM aged 40–80 years diagnosed during 2000–2003 and two times-number (n = 51,806) age- and sex-matched comparisons during the same period were included. We tracked all individuals from their defined index visits for up to 5 years to detect a new diagnosis of hydrocephalus. Among the 25,903 patients, 9227 cases were newly diagnosed T2DM and 16,676 were pre-existing T2DM patients. During the follow-up period, 27 (0.3 %) of the newly diagnosed T2DM patients, 97 (0.6 %) of the pre-existing T2DM patients and 149 (0.3 %) of the comparison group developed hydrocephalus. The risk of hydrocephalus was significantly increased in patients with pre-existing diabetes but not in patients with newly diagnosed diabetes. Longer duration of type 2 diabetes is associated with an increased risk of the development of hydrocephalus. Further studies to confirm such association and to investigate the causality and mechanism are needed." @default.
- W2210931143 created "2016-06-24" @default.
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- W2210931143 date "2016-04-01" @default.
- W2210931143 modified "2023-09-28" @default.
- W2210931143 title "Type 2 diabetes mellitus and risk of hydrocephalus: A 5year population-based follow-up study in Taiwan" @default.
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- W2210931143 doi "https://doi.org/10.1016/j.jdiacomp.2015.12.026" @default.
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