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- W2211024863 abstract "BACKGROUND: Due to its high efficacy and technical simplicity, percutaneous endoscopic gastrostomy (PEG) has gained wide-spread use. Local infection, occurring in approximately 2% to 39% of procedures, is the most common complication in the short term. Risk factors for local infection are largely unknown and therefore – apart from calculated antibiotic prophylaxis – preventive strategies have yet to be determined. OBJECTIVE: To assess the potential patient- and procedure-related risk factors for peristomal infection following PEG tube placement. METHODS: Potential patient-related (eg, age, sex, diseases, body mass index, concomitant antibiotic therapy) and procedure-related (endoscopist experience, institutional factors, findings on endoscopy) risk factors and their coincidence with local infection, defined as a positive peristomal infection three days after PEG tube placement, were evaluated at two institutions. A standardized antibiotic prophylaxis was not performed. The peristomal infection score was also evaluated in 390 patients. RESULTS: Using a multivariate binary regression analysis, four risk factors were established as relevant for local infection after PEG: clinical institution (OR 6.69; P=0.0001), size of PEG tubes (15 Fr versus 9 Fr; OR 2.12; P=0.05), experience of the endoscopist (more than 100 investigations versus less than 100 investigations; OR 0.54; P=0.05) and the existence of a malignant underlying disease (OR 2.28; P=0.019). CONCLUSIONS: Similar to other endoscopic interventions, local infection as a complication of PEG tube placement depends on the experience of the endoscopist. Institutional factors also play a significant role. Additional risk factors include PEG tube size and underlying diseases. These findings indicate that the local infection after PEG tube placement may be influenced by both endoscopy-associated factors and by the underlying disease status of the patient." @default.
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- W2211024863 date "2008-01-01" @default.
- W2211024863 modified "2023-10-18" @default.
- W2211024863 title "Local Infection after Placement of Percutaneous Endoscopic Gastrostomy Tubes: A Prospective Study Evaluating Risk Factors" @default.
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- W2211024863 doi "https://doi.org/10.1155/2008/530109" @default.
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