Matches in SemOpenAlex for { <https://semopenalex.org/work/W2211069431> ?p ?o ?g. }
- W2211069431 endingPage "227" @default.
- W2211069431 startingPage "219" @default.
- W2211069431 abstract "Daphnia (Daphnia pulex) is a small planktonic crustacean and a key constituent of aquatic ecosystems. It is generally used as a model organism to study environmental toxic problems. In the past decade, genomic and proteomic datasets of Daphnia have been developed. The proteomic dataset allows for the investigation of toxicological effects in the context of “Daphnia proteomics,” resulting in greater insights for toxicological research. To exploit Daphnia for ecotoxicological research, information on the post-translational modification (PTM) of proteins is necessary, as this is a critical regulator of biological processes. Acetylation of lysine (Kac) is a reversible and highly regulated PTM that is associated with diverse biological functions. However, a comprehensive description of Kac in Daphnia is not yet available. To understand the cellular distribution of lysine acetylation in Daphnia, we identified 98 acetylation sites in 65 proteins by immunoprecipitation using an anti-acetyllysine antibody and a liquid chromatography system supported by mass spectroscopy. We identified 28 acetylated sites related to metabolic proteins and six acetylated enzymes associated with the TCA cycle in Daphnia. From GO and KEGG enrichment analyses, we showed that Kac in D. pulex is highly enriched in proteins associated with metabolic processes. Our data provide the first global analysis of Kac in D. pulex and is an important resource for the functional analysis of Kac in this organism." @default.
- W2211069431 created "2016-06-24" @default.
- W2211069431 creator A5023746600 @default.
- W2211069431 creator A5054681353 @default.
- W2211069431 creator A5056126085 @default.
- W2211069431 creator A5058572969 @default.
- W2211069431 creator A5079321727 @default.
- W2211069431 creator A5084666518 @default.
- W2211069431 date "2016-02-01" @default.
- W2211069431 modified "2023-09-25" @default.
- W2211069431 title "Global proteomic analysis of protein acetylation affecting metabolic regulation in Daphnia pulex" @default.
- W2211069431 cites W1533191645 @default.
- W2211069431 cites W1571090306 @default.
- W2211069431 cites W1912401841 @default.
- W2211069431 cites W1966542721 @default.
- W2211069431 cites W1974702564 @default.
- W2211069431 cites W1978842703 @default.
- W2211069431 cites W2009826707 @default.
- W2211069431 cites W2015908435 @default.
- W2211069431 cites W2023010129 @default.
- W2211069431 cites W2029130907 @default.
- W2211069431 cites W2032130575 @default.
- W2211069431 cites W2035911064 @default.
- W2211069431 cites W2046488560 @default.
- W2211069431 cites W2055043387 @default.
- W2211069431 cites W2055984320 @default.
- W2211069431 cites W2064437293 @default.
- W2211069431 cites W2064921878 @default.
- W2211069431 cites W2072144793 @default.
- W2211069431 cites W2080035232 @default.
- W2211069431 cites W2080752012 @default.
- W2211069431 cites W2087714970 @default.
- W2211069431 cites W2097372776 @default.
- W2211069431 cites W2100298862 @default.
- W2211069431 cites W2101065953 @default.
- W2211069431 cites W2101291993 @default.
- W2211069431 cites W2109636763 @default.
- W2211069431 cites W2117096101 @default.
- W2211069431 cites W2131233236 @default.
- W2211069431 cites W2133002450 @default.
- W2211069431 cites W2133704620 @default.
- W2211069431 cites W2137100114 @default.
- W2211069431 cites W2153535004 @default.
- W2211069431 cites W2157658519 @default.
- W2211069431 cites W2158173168 @default.
- W2211069431 cites W2166930907 @default.
- W2211069431 cites W2322270733 @default.
- W2211069431 cites W2331066832 @default.
- W2211069431 cites W2331750930 @default.
- W2211069431 cites W4233437719 @default.
- W2211069431 cites W4294216483 @default.
- W2211069431 doi "https://doi.org/10.1016/j.biochi.2015.12.007" @default.
- W2211069431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26700148" @default.
- W2211069431 hasPublicationYear "2016" @default.
- W2211069431 type Work @default.
- W2211069431 sameAs 2211069431 @default.
- W2211069431 citedByCount "7" @default.
- W2211069431 countsByYear W22110694312016 @default.
- W2211069431 countsByYear W22110694312017 @default.
- W2211069431 countsByYear W22110694312018 @default.
- W2211069431 countsByYear W22110694312019 @default.
- W2211069431 countsByYear W22110694312020 @default.
- W2211069431 crossrefType "journal-article" @default.
- W2211069431 hasAuthorship W2211069431A5023746600 @default.
- W2211069431 hasAuthorship W2211069431A5054681353 @default.
- W2211069431 hasAuthorship W2211069431A5056126085 @default.
- W2211069431 hasAuthorship W2211069431A5058572969 @default.
- W2211069431 hasAuthorship W2211069431A5079321727 @default.
- W2211069431 hasAuthorship W2211069431A5084666518 @default.
- W2211069431 hasConcept C104317684 @default.
- W2211069431 hasConcept C104397665 @default.
- W2211069431 hasConcept C119157956 @default.
- W2211069431 hasConcept C135870905 @default.
- W2211069431 hasConcept C137858568 @default.
- W2211069431 hasConcept C18903297 @default.
- W2211069431 hasConcept C19843653 @default.
- W2211069431 hasConcept C2776987104 @default.
- W2211069431 hasConcept C2777477808 @default.
- W2211069431 hasConcept C2778208666 @default.
- W2211069431 hasConcept C2779765374 @default.
- W2211069431 hasConcept C2780187675 @default.
- W2211069431 hasConcept C46111723 @default.
- W2211069431 hasConcept C54355233 @default.
- W2211069431 hasConcept C55493867 @default.
- W2211069431 hasConcept C84766238 @default.
- W2211069431 hasConcept C86803240 @default.
- W2211069431 hasConceptScore W2211069431C104317684 @default.
- W2211069431 hasConceptScore W2211069431C104397665 @default.
- W2211069431 hasConceptScore W2211069431C119157956 @default.
- W2211069431 hasConceptScore W2211069431C135870905 @default.
- W2211069431 hasConceptScore W2211069431C137858568 @default.
- W2211069431 hasConceptScore W2211069431C18903297 @default.
- W2211069431 hasConceptScore W2211069431C19843653 @default.
- W2211069431 hasConceptScore W2211069431C2776987104 @default.
- W2211069431 hasConceptScore W2211069431C2777477808 @default.
- W2211069431 hasConceptScore W2211069431C2778208666 @default.
- W2211069431 hasConceptScore W2211069431C2779765374 @default.
- W2211069431 hasConceptScore W2211069431C2780187675 @default.