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- W2211513709 abstract "Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of motor neurons, resulting in worsening weakness of voluntary muscles until death occurs from respiratory failure. The incidence of ALS in European populations is two to three people per year per 100,000 of the general population. In Europe, crude prevalences range from 1.1/100,000 population in Yugoslavia to 8.2/100,000 in the Faroe Islands. Major advances have been made in our understanding of the genetic causes of ALS, whereas the contribution of environmental factors has been more difficult to assess and large-scale studies have not yet revealed a replicable, definitive environmental risk factor. The only established risk factors to date are older age, male gender and a family history of ALS. Median survival time from onset to death is usually 3 years from the first appearance of symptoms. Older age and bulbar onset are consistently reported to have poorer outcomes. However, there are conflicting data regarding gender, diagnostic delay and El Escorial criteria. The rate of symptom progression has been revealed to be an independent prognostic factor. Psychosocial factors and impaired cognitive function are negatively related to ALS outcome, while nutritional status and respiratory function are also related to ALS prognosis. The effect of enteral nutrition on survival is still unclear, although noninvasive positive pressure ventilation (NIPPV) has been found to improve survival. These findings have relevant implications for the design of future trials." @default.
- W2211513709 created "2016-06-24" @default.
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- W2211513709 date "2016-01-01" @default.
- W2211513709 modified "2023-10-10" @default.
- W2211513709 title "Epidemiology of amyotrophic lateral sclerosis: A review of literature" @default.
- W2211513709 cites W1517808172 @default.
- W2211513709 cites W1548119650 @default.
- W2211513709 cites W1608778639 @default.
- W2211513709 cites W1619082318 @default.
- W2211513709 cites W1680107906 @default.
- W2211513709 cites W1953262130 @default.
- W2211513709 cites W1960193404 @default.
- W2211513709 cites W1964177214 @default.
- W2211513709 cites W1964934303 @default.
- W2211513709 cites W1965638771 @default.
- W2211513709 cites W1971131806 @default.
- W2211513709 cites W1974240968 @default.
- W2211513709 cites W1977988586 @default.
- W2211513709 cites W1978137556 @default.
- W2211513709 cites W1978168248 @default.
- W2211513709 cites W1979370443 @default.
- W2211513709 cites W1981295136 @default.
- W2211513709 cites W1981536765 @default.
- W2211513709 cites W1988344292 @default.
- W2211513709 cites W1988789526 @default.
- W2211513709 cites W1999138692 @default.
- W2211513709 cites W2001432662 @default.
- W2211513709 cites W2003618511 @default.
- W2211513709 cites W2003892877 @default.
- W2211513709 cites W2007478642 @default.
- W2211513709 cites W2008274837 @default.
- W2211513709 cites W2016574024 @default.
- W2211513709 cites W2022026916 @default.
- W2211513709 cites W2022823045 @default.
- W2211513709 cites W2027616313 @default.
- W2211513709 cites W2027642829 @default.
- W2211513709 cites W2028803746 @default.
- W2211513709 cites W2031713384 @default.
- W2211513709 cites W2038915422 @default.
- W2211513709 cites W2044198000 @default.
- W2211513709 cites W2044638372 @default.
- W2211513709 cites W2047435344 @default.
- W2211513709 cites W2050626075 @default.
- W2211513709 cites W2055456084 @default.
- W2211513709 cites W2057769638 @default.
- W2211513709 cites W2058706869 @default.
- W2211513709 cites W2059169811 @default.
- W2211513709 cites W2066002405 @default.
- W2211513709 cites W2066996015 @default.
- W2211513709 cites W2067764900 @default.
- W2211513709 cites W2069436181 @default.
- W2211513709 cites W2075324214 @default.
- W2211513709 cites W2078192516 @default.
- W2211513709 cites W2080802641 @default.
- W2211513709 cites W2082078064 @default.
- W2211513709 cites W2088195560 @default.
- W2211513709 cites W2090573157 @default.
- W2211513709 cites W2097178513 @default.
- W2211513709 cites W2107339266 @default.
- W2211513709 cites W2108949606 @default.
- W2211513709 cites W2111377404 @default.
- W2211513709 cites W2116710635 @default.
- W2211513709 cites W2117991410 @default.
- W2211513709 cites W2122716077 @default.
- W2211513709 cites W2123676540 @default.
- W2211513709 cites W2126824828 @default.
- W2211513709 cites W2128637198 @default.
- W2211513709 cites W2131284986 @default.
- W2211513709 cites W2131461502 @default.
- W2211513709 cites W2133305315 @default.
- W2211513709 cites W2136723087 @default.
- W2211513709 cites W2140595389 @default.
- W2211513709 cites W2154865054 @default.
- W2211513709 cites W2155221045 @default.
- W2211513709 cites W2164229456 @default.
- W2211513709 cites W2167105734 @default.
- W2211513709 cites W2321483327 @default.
- W2211513709 cites W43394866 @default.
- W2211513709 doi "https://doi.org/10.1016/j.neurol.2015.11.002" @default.
- W2211513709 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26727307" @default.
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