FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2211725812> ?p ?o ?g. }

• W2211725812 endingPage "1024" @default.
• W2211725812 startingPage "1015" @default.
• W2211725812 abstract "The endogenous oxytocin system has emerged as an inhibitor of drug-seeking and stress in preclinical models.The goal of this study was to examine whether systemic oxytocin administration attenuated methamphetamine (METH)-seeking in rats pre-exposed to a predator odor threat.In Experiment 1, rats were exposed for 5 days to the predator odor, 2,5-dihydro-2,4,5-trimethylthiazoline (TMT), or saline before METH self-administration began. After extinction training, rats were injected with 1 mg/kg, ip oxytocin (OXT) or saline 30 min before a cue-induced reinstatement test followed by re-extinction and a TMT-induced reinstatement test. In Experiment 2, TMT pre-exposure was followed by 10 days of 1 mg/kg OXT or saline injections before METH self-administration, extinction, and a TMT-induced reinstatement test.In Experiment 1, TMT pre-exposed rats that were injected with saline 30 min before reinstatement exhibited greater drug-seeking induced by conditioned cues or TMT than that exhibited by saline pre-exposed rats. A single injection of OXT 30 min before reinstatement suppressed METH-seeking in both saline- and TMT pre-exposed rats. In Experiment 2, TMT pre-exposed rats that received saline injections for 10 days prior to METH self-administration exhibited enhanced drug-seeking induced by TMT during stress-induced reinstatement. OXT injections for 10 days prior to METH self-administration blocked only the stress-induced exacerbation of drug-seeking in TMT pre-exposed rats.These results support further research on the development of oxytocin as a novel therapeutic drug that has enduring effects on drug-seeking exacerbated by stress." @default.
• W2211725812 created "2016-06-24" @default.
• W2211725812 creator A5008059040 @default.
• W2211725812 creator A5021211592 @default.
• W2211725812 creator A5063209753 @default.
• W2211725812 date "2015-12-23" @default.
• W2211725812 modified "2023-09-24" @default.
• W2211725812 title "Effects of oxytocin on methamphetamine-seeking exacerbated by predator odor pre-exposure in rats" @default.
• W2211725812 cites W1524178766 @default.
• W2211725812 cites W1570177053 @default.
• W2211725812 cites W1649329754 @default.
• W2211725812 cites W1898877040 @default.
• W2211725812 cites W1964277548 @default.
• W2211725812 cites W1966113410 @default.
• W2211725812 cites W1974671535 @default.
• W2211725812 cites W1985605151 @default.
• W2211725812 cites W1988936968 @default.
• W2211725812 cites W1990650114 @default.
• W2211725812 cites W1991163868 @default.
• W2211725812 cites W1993364340 @default.
• W2211725812 cites W1996912271 @default.
• W2211725812 cites W1998893802 @default.
• W2211725812 cites W2001923023 @default.
• W2211725812 cites W2007859385 @default.
• W2211725812 cites W2009542179 @default.
• W2211725812 cites W2024312106 @default.
• W2211725812 cites W2026836897 @default.
• W2211725812 cites W2029231688 @default.
• W2211725812 cites W2031956214 @default.
• W2211725812 cites W2032212320 @default.
• W2211725812 cites W2033202808 @default.
• W2211725812 cites W2034928212 @default.
• W2211725812 cites W2036315082 @default.
• W2211725812 cites W2036572142 @default.
• W2211725812 cites W2039000755 @default.
• W2211725812 cites W2039695354 @default.
• W2211725812 cites W2042192848 @default.
• W2211725812 cites W2051346624 @default.
• W2211725812 cites W2069300470 @default.
• W2211725812 cites W2076518235 @default.
• W2211725812 cites W2079132290 @default.
• W2211725812 cites W2081418461 @default.
• W2211725812 cites W2086264205 @default.
• W2211725812 cites W2090086966 @default.
• W2211725812 cites W2090225504 @default.
• W2211725812 cites W2091857612 @default.
• W2211725812 cites W2093922373 @default.
• W2211725812 cites W2095069422 @default.
• W2211725812 cites W2099753904 @default.
• W2211725812 cites W2102490794 @default.
• W2211725812 cites W2114214919 @default.
• W2211725812 cites W2121748618 @default.
• W2211725812 cites W2130079646 @default.
• W2211725812 cites W2149707217 @default.
• W2211725812 cites W2157095700 @default.
• W2211725812 cites W2162459454 @default.
• W2211725812 cites W2163888128 @default.
• W2211725812 cites W2168836182 @default.
• W2211725812 cites W2170135464 @default.
• W2211725812 cites W2293876729 @default.
• W2211725812 cites W4247665917 @default.
• W2211725812 cites W94898649 @default.
• W2211725812 doi "https://doi.org/10.1007/s00213-015-4184-7" @default.
• W2211725812 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5003622" @default.
• W2211725812 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26700240" @default.
• W2211725812 hasPublicationYear "2015" @default.
• W2211725812 type Work @default.
• W2211725812 sameAs 2211725812 @default.
• W2211725812 citedByCount "28" @default.
• W2211725812 countsByYear W22117258122017 @default.
• W2211725812 countsByYear W22117258122018 @default.
• W2211725812 countsByYear W22117258122019 @default.
• W2211725812 countsByYear W22117258122020 @default.
• W2211725812 countsByYear W22117258122021 @default.
• W2211725812 countsByYear W22117258122022 @default.
• W2211725812 countsByYear W22117258122023 @default.
• W2211725812 crossrefType "journal-article" @default.
• W2211725812 hasAuthorship W2211725812A5008059040 @default.
• W2211725812 hasAuthorship W2211725812A5021211592 @default.
• W2211725812 hasAuthorship W2211725812A5063209753 @default.
• W2211725812 hasBestOaLocation W22117258122 @default.
• W2211725812 hasConcept C101991246 @default.
• W2211725812 hasConcept C126322002 @default.
• W2211725812 hasConcept C15744967 @default.
• W2211725812 hasConcept C166940927 @default.
• W2211725812 hasConcept C169760540 @default.
• W2211725812 hasConcept C178790620 @default.
• W2211725812 hasConcept C185592680 @default.
• W2211725812 hasConcept C199289684 @default.
• W2211725812 hasConcept C2776176026 @default.
• W2211725812 hasConcept C2777193897 @default.
• W2211725812 hasConcept C2777397205 @default.
• W2211725812 hasConcept C2778555786 @default.
• W2211725812 hasConcept C2778916471 @default.
• W2211725812 hasConcept C2779989194 @default.
• W2211725812 hasConcept C2780114369 @default.
• W2211725812 hasConcept C2780376393 @default.
• W2211725812 hasConcept C42219234 @default.

• next