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- W2211892365 abstract "Ethanol elicited a biphasic effects on the extracellular noradrenaline (NA) concentrations in the rat frontal cortex, as assessed by microdialysis in awake animals. A low dose of ethanol (0.2 g/kg i.p.) raised NA output to about 160% of baseline levels. In contrast, a dose of 2 g/kg inhibited NA output to about 70% of pre-drug levels. These results suggest that the decrease in cortical NA output may reflect the sedative-hypnotic properties of ethanol at high doses, whereas the stimulation of extraneuronal NA may represent a biochemical correlate of the arousal and increased alertness elicited by low doses of ethanol." @default.
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- W2211892365 date "1992-09-01" @default.
- W2211892365 modified "2023-09-28" @default.
- W2211892365 title "RAPID COMMUNICATION: BIPHASIC EFFECT OF ETHANOL ON NORADRENALINE RELEASE IN THE FRONTAL CORTEX OF AWAKE RATS" @default.
- W2211892365 doi "https://doi.org/10.1093/oxfordjournals.alcalc.a045282" @default.
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