Matches in SemOpenAlex for { <https://semopenalex.org/work/W2211969541> ?p ?o ?g. }
- W2211969541 endingPage "1590" @default.
- W2211969541 startingPage "1585" @default.
- W2211969541 abstract "Gold nanoparticles have been widely utilized to achieve colorimetric detection for various diagnostic applications. One of the most frequently used methods for DNA detection involves the aggregation of DNA-modified gold nanoparticles driven by target DNA hybridization. This process, however, is intrinsically slow, limiting its use in rapid diagnostics. Here we take advantage of the reverse process: the disassembly of preformed aggregates triggered by the addition of target DNA via a strand displacement mechanism. A systematic study of the dependence of the disassembly rate on temperature, with and without toeholds, has delivered a system that produces an extremely rapid colorimetric response. Furthermore, using an optimal toehold length of 5 nucleotides, target triggered disassembly is rapid over a wide range of ambient temperatures. Using this overhang system, simple visualization of low picomole amounts of target DNA is possible within 10 min at room temperature." @default.
- W2211969541 created "2016-06-24" @default.
- W2211969541 creator A5039175660 @default.
- W2211969541 creator A5047915641 @default.
- W2211969541 creator A5061262845 @default.
- W2211969541 creator A5063832532 @default.
- W2211969541 creator A5072932605 @default.
- W2211969541 creator A5077850313 @default.
- W2211969541 creator A5082238206 @default.
- W2211969541 date "2016-02-02" @default.
- W2211969541 modified "2023-10-17" @default.
- W2211969541 title "Tuning Toehold Length and Temperature to Achieve Rapid, Colorimetric Detection of DNA from the Disassembly of DNA–Gold Nanoparticle Aggregates" @default.
- W2211969541 cites W1748737970 @default.
- W2211969541 cites W1937197262 @default.
- W2211969541 cites W1971856779 @default.
- W2211969541 cites W1972386236 @default.
- W2211969541 cites W1973899622 @default.
- W2211969541 cites W1977125458 @default.
- W2211969541 cites W1979232921 @default.
- W2211969541 cites W1981270649 @default.
- W2211969541 cites W1987565198 @default.
- W2211969541 cites W1988214044 @default.
- W2211969541 cites W1994843698 @default.
- W2211969541 cites W1994986101 @default.
- W2211969541 cites W1998560777 @default.
- W2211969541 cites W1999091059 @default.
- W2211969541 cites W2015440560 @default.
- W2211969541 cites W2015709186 @default.
- W2211969541 cites W2020332697 @default.
- W2211969541 cites W2020777766 @default.
- W2211969541 cites W2043381968 @default.
- W2211969541 cites W2052566608 @default.
- W2211969541 cites W2057317821 @default.
- W2211969541 cites W2064250628 @default.
- W2211969541 cites W2065172677 @default.
- W2211969541 cites W2068350472 @default.
- W2211969541 cites W2078820160 @default.
- W2211969541 cites W2082607189 @default.
- W2211969541 cites W2094107695 @default.
- W2211969541 cites W2133608216 @default.
- W2211969541 cites W2160312052 @default.
- W2211969541 cites W2163451322 @default.
- W2211969541 cites W2170347395 @default.
- W2211969541 cites W2324698777 @default.
- W2211969541 cites W2327119459 @default.
- W2211969541 cites W2418706095 @default.
- W2211969541 cites W2615152981 @default.
- W2211969541 doi "https://doi.org/10.1021/acs.langmuir.5b03777" @default.
- W2211969541 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26707736" @default.
- W2211969541 hasPublicationYear "2016" @default.
- W2211969541 type Work @default.
- W2211969541 sameAs 2211969541 @default.
- W2211969541 citedByCount "28" @default.
- W2211969541 countsByYear W22119695412016 @default.
- W2211969541 countsByYear W22119695412017 @default.
- W2211969541 countsByYear W22119695412018 @default.
- W2211969541 countsByYear W22119695412019 @default.
- W2211969541 countsByYear W22119695412020 @default.
- W2211969541 countsByYear W22119695412021 @default.
- W2211969541 countsByYear W22119695412022 @default.
- W2211969541 countsByYear W22119695412023 @default.
- W2211969541 crossrefType "journal-article" @default.
- W2211969541 hasAuthorship W2211969541A5039175660 @default.
- W2211969541 hasAuthorship W2211969541A5047915641 @default.
- W2211969541 hasAuthorship W2211969541A5061262845 @default.
- W2211969541 hasAuthorship W2211969541A5063832532 @default.
- W2211969541 hasAuthorship W2211969541A5072932605 @default.
- W2211969541 hasAuthorship W2211969541A5077850313 @default.
- W2211969541 hasAuthorship W2211969541A5082238206 @default.
- W2211969541 hasConcept C104819515 @default.
- W2211969541 hasConcept C12554922 @default.
- W2211969541 hasConcept C127413603 @default.
- W2211969541 hasConcept C129275984 @default.
- W2211969541 hasConcept C155672457 @default.
- W2211969541 hasConcept C171250308 @default.
- W2211969541 hasConcept C185592680 @default.
- W2211969541 hasConcept C188198153 @default.
- W2211969541 hasConcept C192562407 @default.
- W2211969541 hasConcept C552990157 @default.
- W2211969541 hasConcept C55493867 @default.
- W2211969541 hasConcept C78519656 @default.
- W2211969541 hasConcept C86803240 @default.
- W2211969541 hasConceptScore W2211969541C104819515 @default.
- W2211969541 hasConceptScore W2211969541C12554922 @default.
- W2211969541 hasConceptScore W2211969541C127413603 @default.
- W2211969541 hasConceptScore W2211969541C129275984 @default.
- W2211969541 hasConceptScore W2211969541C155672457 @default.
- W2211969541 hasConceptScore W2211969541C171250308 @default.
- W2211969541 hasConceptScore W2211969541C185592680 @default.
- W2211969541 hasConceptScore W2211969541C188198153 @default.
- W2211969541 hasConceptScore W2211969541C192562407 @default.
- W2211969541 hasConceptScore W2211969541C552990157 @default.
- W2211969541 hasConceptScore W2211969541C55493867 @default.
- W2211969541 hasConceptScore W2211969541C78519656 @default.
- W2211969541 hasConceptScore W2211969541C86803240 @default.
- W2211969541 hasFunder F4320306151 @default.
- W2211969541 hasFunder F4320322921 @default.
- W2211969541 hasIssue "6" @default.